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2 362 583

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(51)

IPC

A61K39/00(2006-01-01)

(21) (22)

Application

2008113225/13, 2008-04-08

(24)

Start date

2008-04-08

(22)

Actual filing date

2008-04-08

(45)

Published

2009-07-27

(72)

Inventor

Zatsepina Ol'Ga VladimirovnaMalysheva Marina Vladimirovna

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Nauk Institut Bioorganicheskoj Khimii Im. Akademikov M.M. Shemjakina I Ju.A. Ovchinnikova Ran

WAY OF FIXATION OF HUMAN CELLS HeLa AND HEp-2 FOR IMMUNOTCYTOCHEMICAL REVEALING OF CORE AUTOANTIGENS Russian patent published in 2009 - IPC A61K39/00

Abstract RU 2362583 C1

FIELD: medicine.

SUBSTANCE: way of fixation of the human cells HeLa and HEp-2 for immunocytochemical revealing by autoimmune serums of core autoantigens in reaction of indirect immunofluorescence is developed. The preparations fixed in such manner, are stored during long period without loss of antigenic properties and ability to immuno-labeling by autoimmune serums.

EFFECT: invention can be used for creation of domestic preparations for primary screening of autoimmune serums in clinico-laboratory diagnostics of organo-nonspecific human autoimmune diseases.

4 dwg, 2 ex

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RU 2 362 583 C1

Authors

Zatsepina Ol'Ga Vladimirovna

Malysheva Marina Vladimirovna

Dates

2009-07-27—Published

2008-04-08—Filed