DIAZABICYCLIC ARYL DERIVATIVES AS LIGANDS OF NICOTINIC ACETYLCHOLINE RECEPTORS Russian patent published in 2009 - IPC C07D487/08 C07D471/08 A61K31/4995 A61K31/551 A61P25/00 

Abstract RU 2367665 C2

FIELD: medicine.

SUBSTANCE: there are described new diazabicyclic aryl derivatives of general formula (I), where A', A", L and B, n possess the values as specified in the description which are cholinergic ligands to nicotinic acetylcholine receptors, as well as a based pharmaceutical composition. Owing to their pharmacological profile, the compound according to the invention, can be effective in treating such various diseases or disorders, as those associated with the cholinergic system of central nervous system (CNS), peripheral nervous system (PNS), as those associated with plain muscle contraction, endocrine diseases or disorders, neurodegenerative diseases or disorders, diseases or disorders involving inflammation, pain and abstinence symptoms caused by termination of abusing the chemical substances.

EFFECT: effective with regard to various diseases.

16 cl, 3 ex, 1 tbl

Similar patents RU2367665C2

Title Year Author Number
NEW DIAZABICYCLIC ARYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE 2004
  • Peters Dan
  • Ol'Sen Gunnar M.
  • Nil'Sen Ehl'Sebet Ehstergor
  • Jorgensen Tino Djuring
  • Aring Filip K.
RU2338746C2
DIAZABICYCLIC ARYL DERIVATIVES USED AS MODULATORS OF CHOLINERGIC RECEPTORS 2005
  • Peters Dan
  • Ol'Sen Gunnar M.
  • Nil'Sen Ehl'Sebet Ehstergord
  • Ergensen Tino Djukhring
  • Timmerman Daniel' B.
RU2368614C2
NEW 1,4-DIAZA-BICYCLO[3,2,2]NONYL-OXADIAZOLYL DERIVATIVES AND THEIR MEDICAL APPLICATION 2007
  • Peters Dan
  • Ol'Sen Gunnar M.
  • Nel'Sen Ehl'Sebet Ehstergord
  • Timmermann Daniehl' B.
  • Lokhel' Stiven Charl'Z
RU2427581C2
NOVEL DERIVATIVES OF 1,4-DIAZABICYCLOALKANE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 2003
  • Peters Dan
  • Ol'Sen Gunnar M.
  • Nil'Sen Ehlsbet Ostergor
  • Jorgensen Tino Djuring
  • Akhring Filip K.
RU2323218C2
TRICYCLIC COMPOUNDS, METHODS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION AND TREATMENT METHOD 1998
  • Duzha Dzhon Pol
  • Chehn Piter Sinchun
  • Olbrajt Dzhej Donal'D
  • Behgli Dzhekhehn Frehmroz
  • Fehjlli Amedeo Arturo
  • Ehshvell Mark Ehntoni
  • Molinari Al'Bert Dzhon
  • Kadzhjano Tomas Dzhozef
  • Tribul'Ski Judzhin Dzhon
RU2213094C2
8-AMINO-[1,2,4]TRIAZOLO-[1,5-A]PYRIDINE-6-CARBOXYLIC ACID AMIDE AND MEDICINAL AGENT COMPRISING THEREOF 2002
  • Nettekoven Mattias Genrikh
  • Shmitt Sebast'En
RU2296763C2
SPECIFIC GLYCOCOTRICOSTEROID COMPOUND WITH ANTIINFLAMMATORY EFFECT 2004
  • Biggadajk Kejt
  • Dzhon Meht'Ju Piter
  • Nidkham Debora
RU2348645C2
BENZOTHIAZOL DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS 2004
  • Flor Aleksander
  • Jakob-Retne Roland
  • Norkross Rodzher Dejvid
  • Rimer Klaus
RU2351597C2
2-PHENYLAMINOPYRIMIDINE DERIVATIVES AS LEUCINE-RICH REPEAT KINASE 2 (LRRK2) MODULATORS FOR TREATMENT OF PARKINSON'S DISEASE 2012
  • Bejker-Glenn Charlz
  • Berdik Daniel Dzhon
  • Chembers Mark
  • Chan Brajan K.
  • Chen Khuejfen
  • Estrada Entoni
  • Ganzner-Toste Dzhanet
  • Shor Daniel
  • Svini Zakari
  • Van Shumej
  • Chzhao Gujlin
RU2661197C2
BENZOTHIAZOLE DERIVATIVES AND THEIR APPLICATION IN TREATMENT OF DISEASES RELATED TO ADENOSINE A RECEPTORS 2004
  • Flor Aleksander
  • Jakob-Retne Roland
  • Norkross Rodzher Dejvid
  • Rimer Klaus
RU2348629C2

RU 2 367 665 C2

Authors

Peters Dan

Ol'Sen Gunnar M.

Nil'Sen Ehl'Sebet Ehstergord

Ergensen Tino Djukhring

Akhring Filip K.

Timmerman Daniel' B.

Dates

2009-09-20Published

2005-02-01Filed