FIELD: medicine.
SUBSTANCE: invention refers to new 1,4-diaza-bicyclo[3.2.2]nonyl-oxadiazolyl derivatives of formula I 
or to their pharmaceutically acceptable salts; where Ar represents a phenyl group substituted by methylene dioxy or ethylene dioxy. Also, the invention refers to a pharmaceutical composition exhibiting cholinergic receptor activity on the basis of said compounds.
EFFECT: what is produced are new compounds and based pharmaceutical composition which can be effective for treating various diseases or disorders, such as those associated with the cholinergic system of the central nervous system, peripheral nervous system, diseases or disorders associated with smooth muscle contracture, endocrine diseases or disorders, neurodegenerative diseases or disorders, inflammatory diseases or disorders, pain and withdrawal syndromes caused by addictive chemical withdrawal.
10 cl, 1 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NEW DIAZABICYCLIC ARYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | 2004 |
|
RU2338746C2 |
| DIAZABICYCLIC ARYL DERIVATIVES AS LIGANDS OF NICOTINIC ACETYLCHOLINE RECEPTORS | 2005 |
|
RU2367665C2 |
| NOVEL DERIVATIVES OF 1,4-DIAZABICYCLOALKANE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 2003 |
|
RU2323218C2 |
| DIAZABICYCLIC ARYL DERIVATIVES USED AS MODULATORS OF CHOLINERGIC RECEPTORS | 2005 |
|
RU2368614C2 |
| 1-AZABICYCLO[3,3,1]NONANES DERIVATIVES | 2005 |
|
RU2445313C2 |
| AMIDES OF DIAZABICYCLOALKANES, SELECTIVE WITH RESPECT TO ACETYLCHOLINE SUBTYPE OF NICOTINE RECEPTORS AND PHARMACEUTIC COMPOSITION AND METHODS OF TREATMENT WITH THEIR APPLICATION | 2007 |
|
RU2448969C2 |
| 1,3,5-TRISUBSTITUTED TRIAZOLE DERIVATIVE | 2008 |
|
RU2476433C2 |
| AMIDES OF DIASABICYCLOALKANES, SELECTIVE WITH RESPECT TO ACETYLCHOLINE SUBTYPE OF NICOTINIC RECEPTORS | 2007 |
|
RU2517693C2 |
| DERIVATIVE OF 8-AZABICYCLO[3,2,1]OCT-2-ENE, METHODS OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION | 1998 |
|
RU2186780C2 |
| RECEPTOR SUBTYPE-SELECTIVE AZABICYCLOALKANE DERIVATIVES | 2008 |
|
RU2417984C1 |
