FIELD: medicine.
SUBSTANCE: there described are diazabicyclic aryl derivatives of general formula I , their enantiomers or any mixture of those enantiomers, or their pharmaceutically acceptable salts, where radical values A, L, B and n are given in the description, and pharmaceutical composition containing the above diazabicyclic aryl derivatives.
EFFECT: new compounds represent cholinergic ligands of nicotinic receptors of acetylcholine and modulators of receptors and carrying agents of monoamines, and can be used for treatment of diseases and illnesses related to cholinergic system of central nervous system and periphery nervous system, which are related to activity of muscles, endocrine diseases, inflammatory diseases, and neurodegenerative diseases.
12 cl, 2 ex, 1 tbl
Title | Year | Author | Number |
---|---|---|---|
NEW DIAZABICYCLIC ARYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | 2004 |
|
RU2338746C2 |
DIAZABICYCLIC ARYL DERIVATIVES AS LIGANDS OF NICOTINIC ACETYLCHOLINE RECEPTORS | 2005 |
|
RU2367665C2 |
PYRIDYLALKENE AND PYRIDYLALKYNE ACID AMIDES, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF ITS PREPARING | 1997 |
|
RU2200734C2 |
2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3,5]NONANE DERIVATIVES AND USE THEREOF AS GHRELIN RECEPTOR ANTAGONISTS OR INVERSE AGONISTS | 2011 |
|
RU2524341C2 |
PHARMACEUTICAL COMPOSITION CONTAINING BENZODIAZEPINE DERIVATIVES AND RSV FUSION PROTEIN INHIBITOR | 2005 |
|
RU2388476C2 |
N- (PHENYLSULPHONYL) BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS | 2017 |
|
RU2744358C2 |
BENZAMIDE COMPOUNDS | 2019 |
|
RU2801647C2 |
N-(PHENYLSULFONYL)BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS | 2017 |
|
RU2722560C1 |
2-ARYLIMIDAZO[1,2-b]PYRIDAZINE,2-PHENYLIMIDAZO[1,2-a]PYRIDINE AND 2-PHENYLIMIDAZO[1,2-a]PYRAZINE DERIVATIVES | 2011 |
|
RU2598385C2 |
NEW 1,4-DIAZA-BICYCLO[3,2,2]NONYL-OXADIAZOLYL DERIVATIVES AND THEIR MEDICAL APPLICATION | 2007 |
|
RU2427581C2 |
Authors
Dates
2009-09-27—Published
2005-02-01—Filed