FIELD: medicine.
SUBSTANCE: invention concerns microbiology and biotechnology. Escherichia and salmonella are cultivated separately in synthetic nutrient medium. Toxin complex is sterilised and detoxified by two detoxifiers, first by 0.2% formalin solution at 40°C for 7 days, then by 0.5% ethonium solution at 41°C for 7 days. Preparations are mixed in equal volumes and further adsorbed on 1-3 mg/ml of aluminium hydroxide. The mix is packaged into vials and sterilised for 20 minutes at 1.0 atmospheres.
EFFECT: obtainment of anatoxin vaccine for prevention of animal colibacillosis and salmonellosis.
4 ex
| Title | Year | Author | Number |
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| METHOD FOR INCREASING BIOCIDAL AND THERAPEUTIC EFFICACY OF STAPHYLOCOCCAL ANATOXIN VACCINE | 2014 |
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| TUBERCULOSIS ANATOXIN MANUFACTURE METHOD | 2008 |
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RU2360697C1 |
