METHOD FOR PRODUCTION OF STAPHYLOCOCCIC ANATOXIN-VACCINE Russian patent published in 2009 - IPC A61K39/85 

FIELD: biotechnologies.

SUBSTANCE: invention is related to the field of microbiology and biotechnology. Staphylococcic anatoxin-vaccine is prodyuced by detoxication of staphylococcic exo- and endotoxins by to detoxifiers - 0.2% of formalin solution for 7-9 days at 40-45°C, and then 0.6±0.1% solution of etonium for 7-9 days at 40-45°C. At the same time complete detoxication of toxins and inactivation of their allergenic properties are performed at practically 100 % of formalin consumption and etonium. Then sorption of staphylococcic anatoxin-vaccine is carried out per 1-3 mg/ml of aluminium hydroxide, and concentration of inactivated toxin-allergens is doubled by decantation of 50±5% of supernatant.

EFFECT: invention is used for faster healing of wounds, treatment of dermatitis, pneumonia of calves, piglets, prophylaxis of birds staphylococcus.

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