METHOD FOR PRODUCTION OF STAPHYLOCOCCIC ANATOXIN-VACCINE Russian patent published in 2009 - IPC A61K39/85 

Abstract RU 2377014 C1

FIELD: biotechnologies.

SUBSTANCE: invention is related to the field of microbiology and biotechnology. Method includes growing staphylococci on synthetic medium, sterilisation, detoxication of soluble toxins complex and sorption on aluminium hydroxide. Detoxifier used is 0.8±0.2% solution of etonium for performance of complete detoxication of 1.0-3.0 mg/ml of soluble staphylococcic toxins at 42-45°C for 10-12 days. Concentration of staphylococcic anatoxin-vaccine is increased twice by decantation of 50% of supernatant after sorption on aluminium hydroxide.

EFFECT: produced anatoxin-vaccine has high efficiency, is harmless.

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RU 2 377 014 C1

Authors

Evglevskij Anatolij Alekseevich

Evglevskij Dmitrij Anatol'Evich

Majstrenko Larisa Anatol'Evna

Dates

2009-12-27Published

2008-04-29Filed