THERMOCHEMORADIATION THERAPY OF OESOPHAGEAL CANCER Russian patent published in 2009 - IPC A61N5/10 A61B18/04 A61F7/00 A61K31/513 A61K31/282 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention concerns medicine, oncology, and can be used for thermochemoradiation therapy of oesophagus cancer. That is ensured by local transoesophageal hyperthermia, gamma-ray teletherapy and chemotherapy as preoperative actions. Herewith gamma-ray therapy is carried out within 2 weeks in average fractionation mode at 3 Gy 5 times a week to total focal dose 30 Gy. Chemotherapy accompanies the whole course of gamma therapy by daily introduction of fluorouracil dosed 300 mg/m² to the central vein in continuous infusion mode and daily intravenous introduction of cisplatin dosed 6 mg/m² daily within 1 hour. Hyperthermia is applied on 4^th, 8^th and 12^th days of gamma therapy immediately before irradiation session at temperature 42-44°C within 60 minutes.

EFFECT: method allows optimising treatment of the patients suffering from oesophagus cancer and improving clinical effectiveness owing to advanced local control.

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