METHOD OF SIMULATING ACUTE POSTSTREPTOCOCCAL GLOMERULONEPHRITIS IN EXPERIMENT Russian patent published in 2009 - IPC G09B23/28 

Abstract RU 2373580 C1

FIELD: medicine.

SUBSTANCE: invention refers to experimental medicine, namely to experimental nephrology and can be used for simulating acute poststreptococcal glomerulonephritis. That is ensures by intraperitoneal introduction of strain Streptococcus pyogenes Dick-I concentrated 109 CFU/ml diluted 1:9 in a load dose 0.5 ml to an outbred albino rat once a day. The following scheme of introduction is maintained - 3 cycles, each consisting of 1, 3, 5 days for immunisation every 2 days.

EFFECT: higher reproducibility, reduced time for experiment and cost of technique; the method is easy-to-implement.

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RU 2 373 580 C1

Authors

Kolomeets Nadezhda Jur'Evna

Kosareva Polina Vladimirovna

Aver'Janova Natal'Ja Ivanovna

Chereshnev Valerij Aleksandrovich

Dates

2009-11-20Published

2008-07-08Filed