METHOD OF EVALUATING DISTRIBUTION OF MECHANICAL STRESS IN BIOLOGICAL TISSUES Russian patent published in 2009 - IPC A61B5/00 

Abstract RU 2373838 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and is intended for evaluation of mechanical stress distribution in biological tissues without any external influence. When carrying out polaroscopy luminescence of examined region with light of wavelength from 280 to 450 nm is induced and distribution of mechanical stress is evaluated as proportional degrees of luminescence polarisation by formula: τ(x,y)~Δn'(x,y) where τ(x,y) is mechanical stress in point with coordinates (x, y), Δn'(x,y) is degree of optic tissue polarisation in point with coordinates (x,y). After that images of fluorescent tissue with different positions of angle of polarization plane of polarization filter are successively formed, then pairs of images, obtained when polarisation planes of polarisation filter are in mutually perpendicular position, are selected, in each point of pair absolute values of difference of luminescence brightness (ΔB) are calculated by formula: where: - absolute values of difference of tissue luminescence brightness in point c with coordinates (x, y) for pair of images, obtained when polarisation planes of polarisation filter are in mutually perpendicular position, is brightness of point with coordinates (x, y) of first image in pair, bα+90(x,y) is brightness of point with coordinates (x, y) of second image in pair, α is polarisation plane angle for first image in pair. Optic polarisation degree for each point is evaluated by formula: where: Δn'(x, y) is optic polarisation degree in point with coordinates (x, y); - absolute values of difference of tissue luminescence brightness in point with coordinates (x, y) for pair of images, obtained when polarisation planes of polarisation filter are in mutually perpendicular position and when polarization plane for first image is in position at angle α; is brightness of point with coordinates (x, y), when polariszation plane of polarisation filter is at angle α.

EFFECT: method provides possibility of adequate evaluation of mechanical stress distribution for carrying out diagnostics and, therefore, selection of treatment tactics.

2 dwg, 2 ex

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RU 2 373 838 C1

Authors

Avetisov Sergej Ehduardovich

Novikov Ivan Aleksandrovich

Bubnova Irina Alekseevna

Siplivyj Vladimir Ivanovich

Antonov Aleksej Anatol'Evich

Grusha Jaroslav Olegovich

Dates

2009-11-27Published

2008-07-08Filed