COMBINED METHOD FOR TREATING DISSEMINATED STOMACH CANCER CASES Russian patent published in 2006 - IPC A61K31/282 A61K31/513 A61P35/00 

Abstract RU 2270677 C2

FIELD: medicine.

SUBSTANCE: method involves applying combined chemotherapy course, after having done palliative surgical intervention like gastrectomy or stomach resection, in two stages. Cysplatin heated to 45°C is introduced at a dose of 30 mg/m2 into the abdominal cavity at the first stage at the fourth day after the operation. The second stage is carried out at the tenth-fourteenth day of postoperative period. Xeloda is per os given at a daily dose of 2500 mg/m2 in two portions for 14 days and Cysplatin is intravenously drop-by-drop introduced at a dose of 50 mg/m2 at the eighth and fifteenth day relative to Xeloda treatment begin. The second stage is repeated with 3 weeks long pauses until disease progressing are observed.

EFFECT: enhanced effectiveness in achieving partial tumor regress and metastasis regress.

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RU 2 270 677 C2

Authors

Popov Dmitrij Nikolaevich

Tuzikov Sergej Aleksandrovich

Afanas'Ev Sergej Gennad'Evich

Dates

2006-02-27Published

2003-03-20Filed