METHOD FOR MAKING DRY SYNBIOTIC PREPARATION Russian patent published in 2009 - IPC A61K35/66 A23K1/165 

FIELD: medicine.

SUBSTANCE: mother culture is prepared by consistent cultivation of lactic microorganisms Lactobacillus acidophilus B 3235, Lactobacillus delbrueckii subsp.bulgaricus B 5788, Bifidobacterium longum AC 1249, Bifidobacterium adolescentis AC 1244, taken in equal proportion on the nutrient medium consisting of the following components, wt %: cow's milk 50, glucose 5-15, lactose 5-15, agar 3-4, water - the rest. Solid state fermentation of the mother culture is carried out on sterilised amaranth flour in the ratio 1:1 at 35-40°C during 4-6 days to produce a semihumid preparation of 2·10⁹ CFU/g and more. The latter is mixed with the sterilised amaranth flour to ensure humidity of the finished preparation 8-12% and of the biotitre 2-10⁸ CFU/g and more.

EFFECT: expressed synbiotic effect of the preparation, growth-stimulation of organism microflora and improvement of intestinal microbiocoenosis.

3 cl, 1 tbl, 3 ex