FIELD: medicine.
SUBSTANCE: invention refers to molecular salt of 4-[(4-methyl-1-piperazinyl) methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide chosen from the group consisting of (D)-tartrate, (L)-tartrate, succinate and malonate, and to a based pharmaceutical composition.
EFFECT: there are produced and described new salts which can find application in medicine, namely in therapy of tumours.
3 cl, 23 ex, 1 tbl
| Title | Year | Author | Number |
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