METHOD OF MODELLING NEOVASCULARISATION OF DISK OF OPTIC NERVE Russian patent published in 2009 - IPC G09B23/28 A61N5/67 

Abstract RU 2375759 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to ophthalmology, and can be used in experimental ophthalmology for modelling neovascularisation of disk of optic nerve to enable estimate of effectiveness of antiangiogenic, antiinflammatory preparations. That is ensured by intravenous introduction of chlorine photosensitiser to a rabbit in a dose 2.5 mg/kg of weight. Ten minutes later disk of optic nerve is exposed to transpupillary laser irradiation. Power density is 200-250 J/cm2, lasing spot diametre is 6 mm.

EFFECT: method provides development of supplemental vessels of disk of optic nerve with pathological vascular wall, and also partial substitution of neural connective tissue.

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RU 2 375 759 C1

Authors

Belyj Jurij Aleksandrovich

Tereshchenko Aleksandr Vladimirovich

Volodin Pavel L'Vovich

Solov'Ev Dmitrij Konstantinovich

Dates

2009-12-10Published

2008-08-12Filed