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2 376 283

(13)

(51)

IPC

C07C251/76(2006-01-01)

C07C249/00(2006-01-01)

C07C251/72(2006-01-01)

C07C251/82(2006-01-01)

A61K31/15(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2007137268/04, 2007-10-10

(24)

Start date

2007-10-10

(22)

Actual filing date

2007-10-10

(45)

Published

2009-12-20

(72)

Inventor

Matveev Aleksandr IvanovichGolovin Evgenij Valer'EvichKlimochkin Jurij NikolaevichLeonova Marina ValentinovnaMoiseev Igor' KonstantinovichBalakhnin Sergej MarkovichSerova Ol'Ga AlekseevnaBormotov Nikolaj IvanovichBelanov Evgenij Fedorovich

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Samarskij Gosudarstvennyj Tekhnicheskij UniversitetFederal'Noe Gosudarstvennoe Uchrezhdenie Nauki Nauchnyj Tsentr Virusologii I Biotekhnologii Federal'Noj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchija Cheloveka Gnts Vb

HYDRAZONES OF AZIDOKETONES OF ALICYCLIC AND ALIPHATIC RANGE, HAVING ANTIVIRAL ACTIVITY Russian patent published in 2009 - IPC C07C251/76 C07C249/00 C07C251/72 C07C251/82 A61K31/15 A61P31/12

Abstract RU 2376283 C2

FIELD: medicine.

SUBSTANCE: invention is related to new hydrazones of azidoketones of alicyclic and aliphatic range, having activity against orthopoviruses, with common formula , where R₁=1-Ad, R₂=3-R-1-Ad (R=OH, 4-tolyl), 2-Ad, H, 4-tolyl, 4-bromine-phenyl, 4-hydroxyphenyl, 4-methoxyphenyl; R₁=3-Br-1-Ad, R₂=1-Ad, NH₂; R₁=tretbutyl, R₂=1-Ad, where Ad-adamantyl.

EFFECT: increased antiviral activity of compounds.

8 tbl, 12 ex

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RU 2 376 283 C2

Authors

Matveev Aleksandr Ivanovich

Golovin Evgenij Valer'Evich

Klimochkin Jurij Nikolaevich

Leonova Marina Valentinovna

Moiseev Igor' Konstantinovich

Balakhnin Sergej Markovich

Serova Ol'Ga Alekseevna

Bormotov Nikolaj Ivanovich

Belanov Evgenij Fedorovich

Dates

2009-12-20—Published

2007-10-10—Filed