Show metadata Hide metadata

(19)

(11)

2 376 283

(13)

(51)

IPC

C07C251/76(2006-01-01)

C07C249/00(2006-01-01)

C07C251/72(2006-01-01)

C07C251/82(2006-01-01)

A61K31/15(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2007137268/04, 2007-10-10

(24)

Start date

2007-10-10

(22)

Actual filing date

2007-10-10

(45)

Published

2009-12-20

(72)

Inventor

Matveev Aleksandr IvanovichGolovin Evgenij Valer'EvichKlimochkin Jurij NikolaevichLeonova Marina ValentinovnaMoiseev Igor' KonstantinovichBalakhnin Sergej MarkovichSerova Ol'Ga AlekseevnaBormotov Nikolaj IvanovichBelanov Evgenij Fedorovich

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Samarskij Gosudarstvennyj Tekhnicheskij UniversitetFederal'Noe Gosudarstvennoe Uchrezhdenie Nauki Nauchnyj Tsentr Virusologii I Biotekhnologii Federal'Noj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchija Cheloveka Gnts Vb

HYDRAZONES OF AZIDOKETONES OF ALICYCLIC AND ALIPHATIC RANGE, HAVING ANTIVIRAL ACTIVITY Russian patent published in 2009 - IPC C07C251/76 C07C249/00 C07C251/72 C07C251/82 A61K31/15 A61P31/12

Abstract RU 2376283 C2

FIELD: medicine.

SUBSTANCE: invention is related to new hydrazones of azidoketones of alicyclic and aliphatic range, having activity against orthopoviruses, with common formula , where R₁=1-Ad, R₂=3-R-1-Ad (R=OH, 4-tolyl), 2-Ad, H, 4-tolyl, 4-bromine-phenyl, 4-hydroxyphenyl, 4-methoxyphenyl; R₁=3-Br-1-Ad, R₂=1-Ad, NH₂; R₁=tretbutyl, R₂=1-Ad, where Ad-adamantyl.

EFFECT: increased antiviral activity of compounds.

8 tbl, 12 ex

Similar patents RU2376283C2

Title	Year	Author	Number
7-[N'-(4-TRIFLUOROMETHYLBENZOLYL)-HYDRAZINOCARBONYL]-TRICYCLO[3.2.2.0]NON-8-ENE-6-CARBOXYLIC ACID, HAVING ANTIVIRAL ACTIVITY	2009	Selivanov Boris Alekseevich Tikhonov Aleksej Jakovlevich Belanov Evgenij Fedorovich Bormotov Nikolaj Ivanovich Balakhnin Sergej Markovich Serova Ol'Ga Alekseevna Svjatchenko Viktor Aleksandrovich Kiselev Nikolaj Nikolaevich Kazachinskaja Elena Ivanovna Loktev Valerij Borisovich Drozdov Il'Ja Gennadievich Stavskij Evgenij Aleksandrovich	RU2412160C1
HYDRATE OF N-{3,5-DIOXO-4-AZATETRACYCLO[5.3.2.0.0]DODEC-11-EN-4-YL}-2-HYDROXYBENZAMIDE, HAVING ANTIVIRAL ACTIVITY TOWARDS ORTHOPOXVIRUSES	2009	Selivanov Boris Alekseevich Tikhonov Aleksej Jakovlevich Belanov Evgenij Fedorovich Bormotov Nikolaj Ivanovich Balakhnin Sergej Markovich Serova Ol'Ga Alekseevna Svjatchenko Viktor Aleksandrovich Kiselev Nikolaj Nikolaevich Kazachinskaja Elena Ivanovna Loktev Valerij Borisovich Drozdov Il'Ja Gennadievich Stavskij Evgenij Aleksandrovich	RU2412168C1
AMIDES CONTAINING ADAMANTANE AND AROMATIC MOIETIES USED AS INHIBITORS OF ORTHOPOXVIRUS REPRODUCTION	2021	Volcho Konstantin Petrovich Salakhutdinov Nariman Faridovich Suslov Evgenij Vladimirovich Yarovaya Olga Ivanovna Mozhajtsev Evgenij Sergeevich Rastrepaeva Darya Alekseevna Bormotov Nikolaj Ivanovich Shishkina Larisa Nikolaevna Serova Olga Alekseevna Agafonov Aleksandr Petrovich Maksyutov Rinat Amirovich Vernigora Andrej Aleksandrovich Davidenko Andrej Vladimirovich Brunilin Roman Vladimirovich	RU2798665C2
N-{3,5-DIOXO-4-AZATETRACYCLO[5.3.2.0.0]DODEC-11-EN-4-YL}-4-HYDROXYBENZAMIDE, ANTIVIRAL MEDICATION, INHIBITING REPLICATION OF VARIOUS SPECIES OF ORTHOPOXVIRUSES	2010	Selivanov Boris Alekseevich Tikhonov Aleksej Jakovlevich Belanov Evgenij Fedorovich Bormotov Nikolaj Ivanovich Balakhnin Sergej Markovich Serova Ol'Ga Alekseevna Svjatchenko Viktor Aleksandrovich Kiselev Nikolaj Nikolaevich Kazachinskaja Elena Ivanovna Loktev Valerij Borisovich	RU2424800C1
METHYL, CHLORO AND NITRO-DERIVATIVES OF N-{3, 5-DIOXO-4-AZATETRACYCLO [5.3.2.0.0]DODEC-11-EN-4-YL}-2-HYDROXYBENZAMIDE - ANTIVIRAL AGENTS INHIBITING REPLICATION OF DIFFERENT TYPES OF ORTHOPOXVIRUSES	2010	Selivanov Boris Alekseevich Tikhonov Aleksej Jakovlevich Belanov Evgenij Fedorovich Bormotov Nikolaj Ivanovich Balakhnin Sergej Markovich Serova Ol'Ga Alekseevna Svjatchenko Viktor Aleksandrovich Kiselev Nikolaj Nikolaevich Kazachinskaja Elena Ivanovna Loktev Valerij Borisovich	RU2440983C1
{3,5-DIOXO-4-AZATETRACYCLO[5.3.2.0.0]DODEC-11-EN-4-YL}THIOUREA, HAVING ANTIVIRAL ACTIVITY TOWARDS ORTHOPOXVIRUSES	2009	Selivanov Boris Alekseevich Tikhonov Aleksej Jakovlevich Belanov Evgenij Fedorovich Bormotov Nikolaj Ivanovich Balakhnin Sergej Markovich Serova Ol'Ga Alekseevna Svjatchenko Viktor Aleksandrovich Kiselev Nikolaj Nikolaevich Kazachinskaja Elena Ivanovna Loktev Valerij Borisovich Drozdov Il'Ja Gennadievich Stavskij Evgenij Aleksandrovich	RU2412167C1
ANTIVIRAL AGENT	2009	Selivanov Boris Alekseevich Tikhonov Aleksej Jakovlevich Belanov Evgenij Fedorovich Bormotov Nikolaj Ivanovich Balakhnin Sergej Markovich Serova Ol'Ga Alekseevna Svjatchenko Viktor Aleksandrovich Kiselev Nikolaj Nikolaevich Kazachinskaja Elena Ivanovna Loktev Valerij Borisovich Drozdov Il'Ja Gennadievich Stavskij Evgenij Aleksandrovich	RU2423359C1
ADAMANTANE AMINO-DERIVATIVES HAVING INFLUENZA VIRUS INHIBITING ACTIVITY	2008	Klimochkin Jurij Nikolaevich Leonova Marina Valentinovna Shirjaev Andrej Konstantinovich Kuznetsov Sergej Aleksandrovich Golovin Evgenij Valer'Evich Skomorokhov Mikhail Jur'Evich Boreko Evgenij Ivanovich Savinova Ol'Ga Vladimirovna Pavlova Natal'Ja Il'Inichna	RU2401263C2
AMIDES WHICH COMBINE ADAMANTANE AND MONOTERPENE FRAGMENTS USED AS ORTHOPOXVIRUS INHIBITORS	2019	Mozhajtsev Evgenij Sergeevich Suslov Evgenij Vladimirovich Bormotov Nikolaj Ivanovich Shishkina Larisa Nikolaevna Yarovaya Olga Ivanovna Volcho Konstantin Petrovich Serova Olga Alekseevna Salakhutdinov Nariman Faridovich Agafonov Aleksandr Petrovich Maksyutov Rinat Amirovich	RU2712135C1
MEDICATED PRODUCT FOR SMALLPOX VIRUS AND METHOD FOR PRODUCING AND USING IT	2013	Shishkina Larisa Nikolaevna Sergeev Aleksandr Nikolaevich Agafonov Aleksandr Petrovich Sergeev Aleksandr Aleksandrovich Kabanov Aleksej Sergeevich Bulychev Leonid Egorovich Sergeev Artemij Aleksandrovich Gorbatovskaja Dar'Ja Olegovna P'Jankov Oleg Viktorovich Bormotov Nikolaj Ivanovich Shchukin Gennadij Ivanovich Selivanov Boris Alekseevich Tikhonov Aleksej Jakovlevich	RU2543338C1

RU 2 376 283 C2

Authors

Matveev Aleksandr Ivanovich

Golovin Evgenij Valer'Evich

Klimochkin Jurij Nikolaevich

Leonova Marina Valentinovna

Moiseev Igor' Konstantinovich

Balakhnin Sergej Markovich

Serova Ol'Ga Alekseevna

Bormotov Nikolaj Ivanovich

Belanov Evgenij Fedorovich

Dates

2009-12-20—Published

2007-10-10—Filed