ADAMANTANE AMINO-DERIVATIVES HAVING INFLUENZA VIRUS INHIBITING ACTIVITY Russian patent published in 2010 - IPC C07D295/96 C07D295/08 C07C211/41 C07C251/44 A61P31/16 

Abstract RU 2401263 C2

FIELD: chemistry.

SUBSTANCE: in adamantane amino-derivatives of general formula (1), R=OH, R1=R2=R3=H, R4=C2H5, X=Cl, n=1 (I); R=Br, R1=R2=R3=H, R4=C2H5, X=Br, n=1 (II); R=OH, R1=R2=H, R3+R4=-CH2CH2CH2CH2-, X=Cl, n=1 (III); R=Br, R1=R2=H, R3+R4=-CH2CH2CH2CH2-, X=Br, n=1 (IV); R=OH, R1=R2=CH3, R3=R4=H, X=CI, n=1 (V); R=CH3, R1=-CH2OH, R2=R3=R4=H, X=Cl, n=1 (VI).

EFFECT: higher antiviral activity of derivatives towards influenza virus.

1 cl, 1 tbl, 9 ex

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RU 2 401 263 C2

Authors

Klimochkin Jurij Nikolaevich

Leonova Marina Valentinovna

Shirjaev Andrej Konstantinovich

Kuznetsov Sergej Aleksandrovich

Golovin Evgenij Valer'Evich

Skomorokhov Mikhail Jur'Evich

Boreko Evgenij Ivanovich

Savinova Ol'Ga Vladimirovna

Pavlova Natal'Ja Il'Inichna

Dates

2010-10-10Published

2008-09-10Filed