FIELD: biotechnologies.
SUBSTANCE: method of selective preparation of 7α-hydroxyandrostens with the help of floccus, includes transformation of Δ5 -androstenes with the help of mycelium Curvularia lunata VKPM F-981 separated and washed from medium. At the same time substrate is used in the form of microchips, or in the complex with cyclodextrins.
EFFECT: yield of end 7-hydroxyproducts - 60-90%.
2 cl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREPARING 14α-HYDROXYDERIVATIVES OF Δ-3,17-DIKETO-ANDROSTENE | 2009 |
|
RU2407800C1 |
| METHOD OF DELTA-3-KETOSTEROIDS 11 BETA-HYDROXYLATION | 2008 |
|
RU2399674C2 |
| STRAIN Rhodococcus erythropolis "ВКПМ" Ac-1740 FOR 9 ALPHA-HYDROXYSTEROIDS | 2007 |
|
RU2351645C1 |
| STRAIN PIMELOBACTER SIMPLEX ELICITING STEROID-1,2-DEHYDROGENASE ACTIVITY | 2001 |
|
RU2215038C2 |
| METHOD FOR PRODUCTION OF ANDROSTA-1,4-DIENE-3,17-DIONE FROM PLANT AND ANIMAL DERIVED STEROLS | 2005 |
|
RU2297455C2 |
| IMMOBILISED BIOCATALYST FOR MICROBIAL BIOTRANSFORMATION OF STEROID COMPOUNDS | 2013 |
|
RU2524434C1 |
| STRAIN OF BACTERIUM MYCOBACTERIUM NEOAURUM AND METHOD FOR ITS USING FOR PREPARING ANDROST-4-ENE-3,17-DIONE FROM VEGETABLE AND ANIMAL STEROLS | 2001 |
|
RU2231553C2 |
| STRAIN OF BACTERIUM MYCOBACTERIUM SMEGMATIS USED FOR OXIDATION OF PLANT AND ANIMAL STEROLS TO ANDROST-4-ENE-3,17-DIONE | 1997 |
|
RU2126837C1 |
| METHOD OF ISOLATION OF CORTICOSTEROIDS FROM CULTURAL FLUID | 1992 |
|
RU2093518C1 |
| METHOD FOR PREPARING ANDROST-4-EN-3,17-DIONE OR THEIR DERIVATIVES FROM STEROL OF VEGETABLE AND ANIMAL ORIGIN | 1998 |
|
RU2205224C2 |
