METHOD FOR PREDICTION OF MELANOMA SEVERITY Russian patent published in 2010 - IPC A61B5/145 G01N1/28 

FIELD: medicine.

SUBSTANCE: invention refers medicine, namely to oncology. To predict skin melanoma severity, an individual prognostic calculation is made by formula: the prognostic factor = 4.74472 + 0.311714*sex + 0.0920974*age - 1.22181*stage of disease - 0.232456*blood group - 2.77509*Rhesus factor + 0.597768*observed ulcerations + 1.27497*observed mitoses - 1.11004*observed lymphoid infiltration - 1.31926*histological tumour type + 0.0719651*tumour thickness - 0.562743*invasion level. The following values are specified for the qualitative indicators: female - 0, male - 1; Rhesus negative - 0, Rhesus positive - 1; observed ulcerations, mitoses, lymphoid infiltration - 1, absence of ulcerations, mitoses, lymphoid infiltration - 0; nodal histological tumour - 1, lentigomelanoma - 2, superficially extending melanoma - 3, epithelioid cell - 4, pigment-free melanoma - 5, several histological types combined - 6. The absolute values are specified to age, invasion level, blood group, melanoma thickness, melanoma stage, according to the standard Roman designations appropriate. If the factor does not exceed 2.2, favourable clinical course of melanoma is predicted, while the factor equal or more than 2.2 shows unfavourable prognosis.

EFFECT: method allows for shortest individual prediction of melanoma severity with using results conventional techniques.

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