FIELD: medicine.
SUBSTANCE: present invention concerns medical products, particularly a nasal pharmaceutical composition for treating or relieving the rhinitis symptoms, containing aqueous suspension of solid particles of fluticasone with the following particle size distribution profile: approximately 10% of particles are smaller than 0.90 microns; approximately 25% of particles are smaller than 1.6 microns; approximately 50% of particles are smaller than 3.2 microns; approximately 75% of particles are smaller than 6.2 microns; approximately 90% of particles are smaller than 10.0 micron; where the composition is available for intranasal introduction in nasal mucosa. Besides the invention relates to the methods of treating said diseases.
EFFECT: composition provides improved therapeutic efficiency at a small dose of fluticasone.
58 cl, 4 dwg, 3 tbl, 1 ex
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Authors
Dates
2010-01-27—Published
2004-03-29—Filed