NASAL PHARMACEUTICAL COMPOSITIONS AND METHODS OF APPLICATION THEREOF Russian patent published in 2010 - IPC A61K9/10 A61K31/57 A61P11/02 

Abstract RU 2380090 C2

FIELD: medicine.

SUBSTANCE: present invention concerns medical products, particularly a nasal pharmaceutical composition for treating or relieving the rhinitis symptoms, containing aqueous suspension of solid particles of fluticasone with the following particle size distribution profile: approximately 10% of particles are smaller than 0.90 microns; approximately 25% of particles are smaller than 1.6 microns; approximately 50% of particles are smaller than 3.2 microns; approximately 75% of particles are smaller than 6.2 microns; approximately 90% of particles are smaller than 10.0 micron; where the composition is available for intranasal introduction in nasal mucosa. Besides the invention relates to the methods of treating said diseases.

EFFECT: composition provides improved therapeutic efficiency at a small dose of fluticasone.

58 cl, 4 dwg, 3 tbl, 1 ex

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RU 2 380 090 C2

Authors

Chaudri Imitjaz

Dates

2010-01-27Published

2004-03-29Filed