Patenton — panteon of patents

(19)

RU

(11)

2 381 216

(13)

C2

(51)

IPC

C07D211/58(2006-01-01)

C07D401/06(2006-01-01)

C07D409/06(2006-01-01)

C07D413/06(2006-01-01)

C07D417/06(2006-01-01)

A61K31/4523(2006-01-01)

A61P11/00(2006-01-01)

A61P17/00(2006-01-01)

A61P19/00(2006-01-01)

A61P29/00(2006-01-01)

A61P37/00(2006-01-01)

(21) (22)

Application

2006146877/04, 2005-06-20

(24)

Start date

2005-06-20

(22)

Actual filing date

2005-06-20

(45)

Published

2010-02-10

(72)

Inventor

Taker Khauard

(73)

Holder

Astrazeneka Ab

CHEMICAL COMPOUNDS I Russian patent published in 2010 - IPC C07D211/58 C07D401/06 C07D409/06 C07D413/06 C07D417/06 A61K31/4523 A61P11/00 A61P17/00 A61P19/00 A61P29/00 A61P37/00 

Abstract RU 2381216 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a novel compound N-(1-{(3R)-3-(3,5-difluorophenyl)-3-[1-(methylsulfonyl) piperidin-4-yl]propyl}piperidin-4-yl)-N-ethyl-2-[4- (methylsufonyl)phenyl]acetamide or its pharmaceutically acceptable salts. The invention also relates to a method for synthesis of the compound in paragraph 1, as well as to a pharmaceutical composition.

EFFECT: obtaining a novel biologically active compound with activity towards CCR5 (chemokine receptor 5).

6 cl, 6 ex, 2 tbl

Similar patents RU2381216C2

Title Year Author Number
PIPERIDINE DERIVATIVES AS MODULATORS OF ACTIVITY OF CCR5 RECEPTOR, METHOD AND INTERMEDIATE COMPOUNDS FOR OBTAINING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 2002
  • Takker Khauard
 RU2345990C2
N-HYDROXYFORMAMIDE COMPOUNDS AS METALLOPROTEINASE INHIBITORS 2004
  • Finlej Moris Rejmond Verschojl
  • Uoterson Dejvid
 RU2351595C2
QUINUCLIDINE DERIVATIVES OF (HETERO) ARYLCYCLOHEPTANE CARBOXYLIC ACIDS AS MUSCARINE RECEPTOR ANTAGONISTS 2007
  • Ford Ronan
  • Mater Ehndrju
  • Mete Antonio
 RU2456286C2
DERIVATIVES OF PHENYLACETIC ACID 2004
  • Bonnert Rodzher Viktor
  • Pejtel Ehnil
  • Tom Stiven
 RU2360901C2
MONO-SODIUM SALT 5-[[(2,3-DIFLUOROPHENYL)METHYL]THIO]-7-[[2-HYDROXY-1-(HYDROXYMETHYL)-1-METHYETHYL]AMINO]-THIAZOLE[4,5-d]PYRIMIDINE-2(3H)-ON AS MODULATOR OF ACTIVENESS OF CHEMOKINE RECEPTORS, ITS APPLICATIONS AND PHARMACEUTICAL COMPOSITION 2003
  • Bonnert Rodzher Viktor
 RU2342389C2
ALKYL SULPHONAMIDE QUINOLINES WITH AFFINITY TO NK-3 RECEPTORS 2006
  • Simpson Tomas
  • Kang Dzhejms
  • Ehlbert Dzheffri
  • Ehlkhambra Kristobal'
  • Kouiter Dzherard
  • Vuds Dzhejms
  • Li Jan
 RU2421447C2
2-PYRAZINONE DERIVATIVES FOR TREATING DISEASES OR CONDITIONS WHERE INHIBITING NEUTROPHIL ELASTASE ACTIVITY IS USEFUL 2007
  • Khansen Peter
  • Ivarsson Marianne
  • Lavitts Karolina
  • Lenn Khans
  • Nikitidis Antonios
  • Raj Asim
 RU2448098C2
NITRIC HETEROCYCLIC DERIVATIVES AND MEDICINAL AGENTS CONTAINING SAID DERIVATIVES AS ACTIVE INGREDIENT 2005
  • Takaoka Esikadzu
  • Sibajama Siro
  • Nisidzava Rena
 RU2409565C2
AMINOTETRAHYDROPYRANES AS DIPEPTIDYLPEPTIDASE-IV INHIBITORS FOR TREATING OR PREVENTING DIABETES 2010
  • Biftu Tesfaje
  • Chehn' Pin
  • Fehn Dan'Tsin
  • Tsjan' Sjaosja
 RU2550508C2
CGRP RECEPTOR ANTAGONISTS 2004
  • Bergi Kristofer S.
  • Dehn Chzhehnu Tsz
  • Ngujen Dim N.
  • Pehuan Dehniel V.
  • Sho Ehntoni U.
  • Uill'Jams Tereza M.
 RU2308458C2

RU 2 381 216 C2

Authors

Taker Khauard

Dates

2010-02-10—Published

2005-06-20—Filed

download Download PDF read Similar patents