FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to compounds of formula (I) 
wherein R4 represents a group of formula (II) 
and R1 , R2, R3, R5 and X are those as specified in the patent claim.
EFFECT: preparing the pharmaceutical composition applicable in treating chronic obstructive pulmonary disease and containing the compound of formula (I).
8 cl, 3 tbl, 39 ex
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