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(19)

(11)

2 382 038

(13)

(51)

IPC

C07D401/14(2006-01-01)

C07D403/14(2006-01-01)

C07D413/14(2006-01-01)

A61K31/496(2006-01-01)

A61P15/06(2006-01-01)

(21) (22)

Application

2007102274/04, 2005-06-21

(24)

Start date

2005-06-21

(22)

Actual filing date

2005-06-21

(45)

Published

2010-02-20

(72)

Inventor

Bortvik Alan DehvidKhiki Dirdre Mehri BernadettLiddl DzhonMehjson Ehndrju Makmartri

(73)

Holder

Glehkso Grup Limited

PIPERAZINE INDOLES AS OXYTOCIN RECEPTOR ANTAGONISTS Russian patent published in 2010 - IPC C07D401/14 C07D403/14 C07D413/14 A61K31/496 A61P15/06

Abstract RU 2382038 C2

FIELD: chemistry.

SUBSTANCE: described are piperazine indoles of general formula , in which R1 represents 2-indanyl, R2 represents 1-methylpropyl, R3 and R4 together with nitrogen atoms to which they are bonded represent a morpholino group, and pharmaceutically acceptable salts thereof. Also described is a pharmaceutical composition based on formula (I) compound.

EFFECT: compounds have antagonistic effect on oxytocin receptor.

6 cl, 1 tbl, 6 ex

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RU 2 382 038 C2

Authors

Bortvik Alan Dehvid

Khiki Dirdre Mehri Bernadett

Liddl Dzhon

Mehjson Ehndrju Makmartri

Dates

2010-02-20—Published

2005-06-21—Filed