FIELD: medicine.
SUBSTANCE: medicinal agent with activity of alpha interferon represents a conjugate with a molecule of branched polyethylene glycol of general formula: , where: INF - polypeptide of alpha interferon; R - radicals of 2-aminoethanol -HN-CH2-CH2-O-, 3-aminopropanol -HN-CH2-CH2-CH2-O-, homoserine -HN-CH(COOH)-CH2-CH2-O-; n and n1 - identical or different =50-170, wherein residual branched polyethylene glycol molecular weight 5000-15000 Da are covalently bound with amino groups of polypeptide of alpha interferon.
EFFECT: said agent is an effective antiviral and antiproliferative preparation.
2 cl, 3 tbl, 9 ex
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Authors
Dates
2010-02-20—Published
2008-12-25—Filed