FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to piridazine derivatives of formula II
,
in which radicals and symbols have determinations, given in the invention formula, or to their pharmaceutically acceptable salts.
EFFECT: compounds of formula II demonstrate inhibiting effect with respect to proteinkinases such as c-met, ron, or ALK, or chimeric proteins, and can be useful for treatment of disorders, associated with abnormal activity of proteinkinases, such as cancer.
7 cl, 1 tbl, 30 ex
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