NOVEL DOPAMINE NEUROTRANSMISSION MODULATORS Russian patent published in 2010 - IPC C07D295/04 C07D295/08 A61K31/4965 A61P25/00 

Abstract RU 2386623 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel 3-substituted 4-(phenyl-N-alkyl)piperazine compounds of formula (1) , where R1 represents OSO2CF3, OSO2CH3, SO2R3, COCF3 and COCH2CH3, R2 represents C1-C4 alkyl or allyl, R3 represents C1-C3 alkyl or CF3, as well as to their pharmaceutically acceptable salts. The disclosed compounds are capable of modulating dopamine neurotransmission.

EFFECT: invention discloses pharmaceutical compositions of compounds which are used for treating disorders of the central nervous system.

4 cl, 24 ex

Similar patents RU2386623C2

Title Year Author Number
3-SUBSTITUTED 4-(PHENYL-N-ALKYL)-PIPERIDINES, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, METHODS FOR TREATMENT 2000
  • Sonesson Klas
  • Uoters Susanna
  • Uoters Nikolas
  • Tedroff Joakim
  • Andersson Bengt
RU2265013C2
SUBSTITUTED 4-(PHENYL-N-ALKYL)PIPERIDINES, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHODS FOR TREATMENT 2000
  • Sonesson Klas
  • Uoters Susanna
  • Uoters Nikolas
  • Tedroff Joakim
  • Andersson Bengt
RU2262504C2
NEW DISUBSTITUTED PHENYL PIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION 2005
  • Sonesson Klas
  • Svanson Lars
  • Uoters Nikolas
RU2366654C2
NEW MODULATORS OF CORTICAL DOPAMINERGIC AND GLUTAMATERGIC NEUROTRANSMISSION MEDIATED BY NMDA-RECEPTOR 2012
  • Sonesson Klas
  • Karlsson Jonas
  • Svensson Peder
RU2593500C2
N-OXIDE AND/OR DI-N-OXIDE DERIVATIVES OF STABILISERS/MODULATORS OF DOPAMINE RECEPTORS, DEMONSTRATING IMPROVED PROFILES OF CARDIO-VASCULAR SIDE EFFECTS 2008
  • Vikstrem Khokan V.
RU2470013C2
3,5-DISUBSTITUTED PHENYL-PYPERIDINES AS DOPAMINE NEUROTRANSMISSION MODULATORS 2006
  • Sonesson Klas
RU2418787C2
3-PHENYL-3-METHOXYPYRROLIDINE DERIVATIVES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION 2009
  • Sonesson Klas
  • Svanson Lars
  • Pettersson Fredrik
RU2524214C2
NEW DERIVATIVES OF HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION, METHOD FOR MODULATION OF AUTOIMMUNE DISEASES, METHOD FOR PREPARING THESE COMPOUNDS 2000
  • Ehmman'Juehl Mishel' Dzh.
  • Fr'E Lija L.
  • Khikki Judzhin R.
  • Lju Vehjmin'
  • Moruik Tina M.
  • Spero Denis M.
  • Sun' Sansin
  • Tomson Dejvid S.
  • Uord Jansi D.
  • Jang Ehrik R.R.
RU2255937C2
DERIVATIVES OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1999
  • Brehnn Mark Robert
  • Messier Terri
  • Karrier Ehrika Ehnn
  • Dadzhento Kataran Lauri
  • Friberg Mikaehl'
  • Sk'Erbek Nil'S
  • Spehlding Trehjsi
RU2230740C2
NOVEL ARYLPIPERAZINYL COMPOUNDS 2004
  • Danoa Dehjl S.
  • Chen' Donli
  • Bekker Oren
  • Nojman Sil'Vija
  • Cheruku Srinivasa Rao
  • Marantts Jaehl
  • Sharadendu Anurag
  • Shachem Sharon
  • Khejfetts Aleksandr
  • Mokhanti Pradiumna
  • Inbal Boaz
  • Fichman Merav
  • Nudel'Man Rafaehl'
  • Bar-Khaim Shaj
RU2339627C2

RU 2 386 623 C2

Authors

Sonesson Klas

Uoters Susanna

Uoters Nikolas

Tedroff Joakim

Andersson Bengt

Dates

2010-04-20Published

2000-12-22Filed