3-SUBSTITUTED 4-(PHENYL-N-ALKYL)-PIPERIDINES, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, METHODS FOR TREATMENT Russian patent published in 2005 - IPC

FIELD: organic chemistry, medicine, neurology, pharmacy.

SUBSTANCE: invention relates to 3-substituted 4-(phenyl-N-alkyl)piperidines of the general formula (1):

wherein R₁ represents -OSO₂CF₃, -OSO₂CH₃, -SOR₃, -SO₂R_{3, -}COR₃; R₂ represents (C₁-C₄)-alkyl, allyl, -CH₂CH₂OCH₃, -CH₂CH₂CH₂F, -CH₂CF₃, 3,3,3-trifluoropropyl, 4,4,4,-trifluorobutyl group; R₃ represents (C₁-C₃)-alkyl, -CF₃, and their pharmaceutically acceptable salts also. Also, invention discloses pharmaceutical compositions of abovementioned compounds and methods wherein abovementioned compounds are used in treatment of the central nervous system disturbances.

EFFECT: improved methods for treatment, valuable medicinal properties of compounds and compositions.

31 cl, 47 ex