DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR HYPOXIA TYPE Russian patent published in 2011 - IPC G01N33/573 G01N33/50 

FIELD: medicine.

SUBSTANCE: blood plasma is analysed for cytochrome oxidase activity, erythrocyte 2,3- biphosphoglycerate and lactic acid concentrations. It is followed by calculating an oxygenation coefficient K by formula: K=(C₁+C₂):A, where C₁ is the erythrocyte 2,3- biphosphoglycerate concentration, mol/l; C₂ is the erythrocyte lactic acid concentration, mol/l; A is plasma cytochrome oxidase activity, mol/l. The K value withint 1.0 <K≤3.0 enables to diagnose tissue hypoxia, while in case of the K values being 3.0<K≤5.0 cardiovascular hypoxia is diagnosed. If the oxygenation coefficient is 5.0 and more, blood hypoxia is diagnosed.

EFFECT: use of the method enables the differential diagnostics of blood, tissue and cardiovascular hypoxia.

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