METHOD FOR SYNTHESIS OF 2-METHYL-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-c][1,5]NAPHTHYRIDINE-4-AMINE Russian patent published in 2010 - IPC C07D471/00 C07D491/00 C07D498/00 C07D513/00 C07D515/00 C07D471/02

Abstract RU 2388760 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to a method for synthesis of 2-methyl-1-(2-methylpropyl)-1H-imidazo[4.5-c][1.5]naphthyridine-4-amine. The method involves the following: 2-methyl-1-(2-methypropyl)-5-oxido-1H-imidazo[4.5-c][1.5]naphthyridine is obtained in a carrier which contains lower alcohol; the 2-methyl-1-(2-methypropyl)-5-oxido-1H-imidazo[4.5-c][1.5]naphthyridine in the carrier is combined with a reagent which contains ammonia or ammonium and arylsulfonyl halide to form a mixture; and components of the mixture can react in a period of time sufficient for formation of 2-methyl-1-(2-methylpropyl)-1H-imidazo[4.5-c][1.5]naphthyridine-4-amine.

EFFECT: obtaining a new compound.

67 cl, 5 ex

Similar patents RU2388760C2

Title	Year	Author	Number
METHOD OF SYNTHESIS OF DERIVATIVES OF 2-CHLORO-NITROQUINOLINEAMINES, METHOD OF SYNTHESIS OF 2-CHLORO-3,4-DIAMINOQUINOLINES, METHOD OF SYNTHESIS OF DERIVATIVES OF 4-CHLORO-1H-IMIDAZO-[4,5-C]-QUINOLINES, METHOD OF SYNTHESIS OF DERIVATIVE OF 1H-IMIDAZO-[4,5-C]-QUINOLINES, 2-CHLORO-3-NITROAMINOQUINOLINE, 2-CHLORO-3,4-DIAMINOQUINOLINE	1990	Andre Zhan-Deni[Fr] Lagan Daniehl' Zhan Mari[Fr]	RU2083563C1
TRANSGLUTAMINASE 2 (TG2) INHIBITORS	2019	Campbell, David Chapman, Justin Cheung, Mui, H. Diraimondo, Thomas, R. Duron, Sergio, G.	RU2781370C2
PYRAZOLAMINOPIRIMIDINE DERIVATIVES AS MODULATORS OF LEUCINE-REPEATING KINASE 2	2013	Bejker-Glenn Charlz Berdik Daniel Dzhon Chembers Mark Chan Brajan K. Chen Khuejfen Estrada Entoni Svini Zakari Kevin	RU2637947C2
PYRAZOLAMINOPIRIMIDINE DERIVATIVES AS LEUCINE-REPEATING KINASE 2 (LRRK2) MODULATORS FOR TREATMENT OF PARKINSON DISEASE	2013	Bejker-Glenn Charlz Chan Brajan K. Dotson Dzhennafer Estrada Entoni Kheffron Timoti Lissikatos Dzhozef Svini Zakari Kevin	RU2637948C2
N-{2-[4-AMINO-2-(ETHOXYMETHYL)-1H-IMIDAZO-[4,5-c]-QUINOLIN-1-YL]-1,1-DIMETHYLETHYL}-METHANESULFONAMIDE AND PHARMACEUTICAL COMPOSITON BASED ON SAID COMPOUND	2004	Griesgraber Dzhordzh V.	RU2374246C2
N4-PHENYLQUINAZOLINE-4-AMINE DERIVATIVES AND RELATED COMPOUNDS AS RECEPTOR TYROSINE KINASE TYPE ERBB INIHIBITORS FOR TREATING HYPERPROLIFERATIVE DISEASES	2006	Lissikatos Dzhozef P. Marmsater Fredrik P. Chao Chzhan' Greschuk Dzhuli Mari Vejdong L'Ju Khennings Dehvid D.	RU2428421C2
IMIDAZOQUINOLINE COMPOUNDS	2005	Valiante Nikolas Ksu Feng Lin Ksiaodong Chu Dehniehl Vang Ksiaozhing Majkl	RU2415857C2
NEW DERIVATIVES OF IMIDAZO [4,5-C] QUINOLINES AND IMIDAZO [4,5-C] [1,5] NAPHTHYRIDINES AS LRRK2 INHIBITORS	2016	Galatsis Paul Henderson Jaclyn Louise Kormos Bethany Lyn Kurumbail Ravi G. Reese Matthew Richard Stepan Antonia Friederike Verhoest Patrick Robert Wager Travis T. Pettersson Martin Youngjin Garnsey Michelle Renee	RU2722149C1
INHIBITORS OF TYPE ErbB INHIBITORS	2006	Lissikatos Dzhozef P. Marmsater Fredrik P. Chao Chzhan Greschuk Dzhuli Mari Vejdong Lyu Khennings Devid D.	RU2592703C9
IMIDAZO[4,5-C]PYRIDINE DERIVATIVES AS TOLL-LIKE RECEPTOR AGONISTS	2020	Ahmad, Omar Fensome, Andrew Fisher, Ethan Lawrence Lachapelle, Erik Alphie Unwalla, Rayomand J Xiao, Jun Zhang, Lei	RU2785124C1

RU 2 388 760 C2

Authors

Marten Jug

Ak David

Tussen Klemen

Djubua Fabris

Dates

2010-05-10—Published

2005-12-28—Filed