FIELD: organic chemistry. SUBSTANCE: products: derivatives of 4-chloro-1H-imidazo-[4,5-c] -quinolines, intermediate compounds for their synthesis. Reagent 1: 2,4-dichloro-3-nitroquinoline. Reagent 2: amine R-NH. Reaction conditions: organic solvent, base and synthesis of the corrersponding chloronitrodiaminoquinoline that is reduced to the corresponding chlorodiaminoquinoline and the latter interacts with trialkylfluoroether. EFFECT: improved method of synthesis. 6 cl
Title | Year | Author | Number |
---|---|---|---|
NEW DERIVATIVES OF IMIDAZO [4,5-C] QUINOLINES AND IMIDAZO [4,5-C] [1,5] NAPHTHYRIDINES AS LRRK2 INHIBITORS | 2016 |
|
RU2722149C1 |
NEW IMIDAZO[4,5-c]QUINOLINE DERIVATIVES AS LRRK2 INHIBITORS | 2018 |
|
RU2773516C2 |
N-{2-[4-AMINO-2-(ETHOXYMETHYL)-1H-IMIDAZO-[4,5-c]-QUINOLIN-1-YL]-1,1-DIMETHYLETHYL}-METHANESULFONAMIDE AND PHARMACEUTICAL COMPOSITON BASED ON SAID COMPOUND | 2004 |
|
RU2374246C2 |
METHOD FOR SYNTHESIS OF 2-METHYL-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-c][1,5]NAPHTHYRIDINE-4-AMINE | 2005 |
|
RU2388760C2 |
IMIDAZO[4,5-C]PYRIDINE DERIVATIVES AS TOLL-LIKE RECEPTOR AGONISTS | 2020 |
|
RU2785124C1 |
DERIVATIVES OF 1,3-DIHYDRO-2H-IMIDAZO[4,5-B]QUINOLINE-2-ONE AS AN INHIBITORS OF PHOSPHODIESTERASE, A METHOD OF ITS SYNTHESIS, INTERMEDIATE COMPOUNDS, A PHARMACEUTICAL COMPOSITION AND A METHOD OF ITS PREPARING | 1992 |
|
RU2127273C1 |
4-AMINO-IMIDAZOQUINOLINE DERIVATIVES, USEFUL IN TREATING DISEASES MEDIATED BY TLR7 AND/OR TLR8 AGONISTS | 2015 |
|
RU2698902C2 |
DERIVATIVES OF 2-BENZOYL-IMIDAZO [1,2-a] PIRIDINE, THEIR PRODUCTION AND THEIR APPLICATION IN THERAPY | 2008 |
|
RU2442785C1 |
DERIVATIVES OF IMIDAZO[1,2-C]PYRIMIDINYL ACETIC ACID | 2005 |
|
RU2373208C2 |
DERIVATIVES OF QUINOLINE-2(1H)-ONE, METHODS OF THEIR SYNTHESIS, DRUG AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 1996 |
|
RU2167874C2 |
Authors
Dates
1997-07-10—Published
1990-10-25—Filed