FIELD: medicine, pharmaceutics.
SUBSTANCE: pharmaceutical composition contains a granulated component including multiple hardened melt granules of sugar alcohol containing salt of nonsteroidal anti-inflammatory drug (NSAID salt). The pharmaceutical composition is used for managing pain and/or inflammation and/or febrilily in coughing, cold, influenza, migraine, headache, rheumatic pain, arthritis pain, muscular pain and/or neuralgia.
EFFECT: according to the invention, the pharmaceutical composition contains minimum of tableting excipients, has improved fluidity, is less sticky, than NSAID salt itself and exhibits preferable tableting, disintegrating and dissolution properties.
39 cl, 3 dwg, 3 tbl, 29 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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| GRANULES CONTAINING PARACETAMOL, NSAID AND SUGAR ALCOHOL PREPARED BY MELT EXTRUSION | 2005 |
|
RU2389478C2 |
| THERAPEUTIC AGENTS | 2000 |
|
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| THERAPEUTIC AGENTS | 2002 |
|
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| IMPROVED STABILITY TABLET CONTAINING AT LEAST TWO ACTIVE INGREDIENTS | 2008 |
|
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|
RU2423997C9 |
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|
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| PHARMACEUTICAL COMPOSITIONS, CONTAINING IMATINIB AND RELEASE MODERATOR | 2006 |
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| METHOD FOR MELT GRANULATION | 2009 |
|
RU2491918C2 |
| METHOD FOR PREPARING SOLID DISPERSIONS OF HIGH CRYSTALLINE THERAPEUTIC COMPOUNDS | 2007 |
|
RU2454220C2 |
