ANTIBODY PURIFICATION METHOD Russian patent published in 2010 - IPC B01J41/04 B01J15/00 C07K16/00 

FIELD: chemistry.

SUBSTANCE: invention relates to biochemistry. A method is proposed for isolating antibodies from other compound(s) in a liquid sample where a mobile phase containing the said sample is brought into contact with a multimodal separation matrix in order to adsorb undesirable compounds, while the antibody remains in the liquid in free state, where the multimodal separation matrix contains first type groups, which can interact with negatively charged sites of target compounds and second type groups which are capable of at least one interaction which is different from charge-charge interaction with the said target compounds. Also proposed is a chromatographic column filled with the multimodal separation matrix described above and a filter which has multimodal groups adsorbed on its surface.

EFFECT: design of an efficient method of isolating antibodies from other compound(s) in a liquid sample.

26 cl, 5 ex, 9 tbl, 20 dwg