PHARMACEUTICAL COMPOSITION CONTAINING TEMOZOLOMIDE ESTER Russian patent published in 2010 - IPC C07D487/04 A61K31/4188 A61P35/00 

Abstract RU 2393160 C2

FIELD: chemistry.

SUBSTANCE: present invention discloses pharmaceutical compositions based on telozolomide-8-carboxylate compounds of general formula I, as well as a method of preparing the said compositions. The disclosed composition has anti-tumour activity and can be especially useful during transdermal application.

EFFECT: obtaining compositions which, along with conventional pharmaceutical carriers, contain a component of acidic nature which gives the pharmaceutical composition high resistance to pH fluctuation.

16 cl, 2 tbl, 21 ex

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RU 2 393 160 C2

Authors

Van Jonfen

Dates

2010-06-27Published

2005-09-15Filed