FIELD: chemistry.
SUBSTANCE: present invention discloses pharmaceutical compositions based on telozolomide-8-carboxylate compounds of general formula I, as well as a method of preparing the said compositions. The disclosed composition has anti-tumour activity and can be especially useful during transdermal application.
EFFECT: obtaining compositions which, along with conventional pharmaceutical carriers, contain a component of acidic nature which gives the pharmaceutical composition high resistance to pH fluctuation.
16 cl, 2 tbl, 21 ex
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Authors
Dates
2010-06-27—Published
2005-09-15—Filed