FIELD: chemistry.
SUBSTANCE: group of inventions relates to organic chemistry and includes an aryl-condensed isoselenazole compound of formula (I), a method for production thereof and use thereof, a pharmaceutical composition containing it, and a method of treatment. In formula (I) A1, A2, A3 and A4 are CH, R1 is C1-6 alkylene, R is selected from hydrogen, halogen, C1-6 alkyl or C1-6 alkoxy.
EFFECT: compound of formula (I), having inhibitory activity on thioredoxin reductase (TrxR).
21 cl, 4 dwg, 7 tbl, 13 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PHARMACEUTICAL COMPOSITION CONTAINING TEMOZOLOMIDE ESTER | 2005 |
|
RU2393160C2 |
| PHTHALAZINE KETONE DERIVATIVE, METHOD OF OBTAINING THEREOF AND PHARMACEUTICAL APPLICATION | 2011 |
|
RU2564527C2 |
| IMIDAZOISOINDOLE DERIVATIVE, METHOD FOR PRODUCTION THEREOF AND MEDICAL USE | 2016 |
|
RU2717577C2 |
| HETEROCYCLIC IMIDAZOLE COMPOUNDS, METHOD FOR THE PRODUCTION AND USE THEREOF | 2016 |
|
RU2686314C1 |
| HETEROARYL COMPOUNDS AS TKB INHIBITORS AND USE THEREOF | 2015 |
|
RU2742122C2 |
| HETEROARYL COMPOUNDS, COMPOSITIONS CONTAINING THEM AND METHODS OF TREATING WITH USE OF SUCH COMPOUNDS | 2007 |
|
RU2478635C2 |
| INHIBITOR CONTAINING A TRICYCLIC DERIVATIVE, A METHOD OF ITS PRODUCTION AND ITS USE | 2019 |
|
RU2800543C2 |
| MACROCYCLIC TYROSINE KINASE INHIBITOR AND ITS USE | 2019 |
|
RU2798231C2 |
| HETEROARYL COMPOUNDS, THEIR COMPOSITIONS AND USE THEREOF AS PROTEIN KINASE INHIBITORS | 2007 |
|
RU2474582C2 |
| TRICYCLIC PYRAZOLOPYRIMIDINE DERIVATIVE | 2010 |
|
RU2520966C2 |
