ARYL-CONDENSED ISOSELENAZOLE COMPOUND CONTAINING TETRAZINE SUBSTITUTE, METHOD FOR PRODUCTION THEREOF AND USE THEREOF Russian patent published in 2024 - IPC C07D487/04 C07D293/12 A61K31/4188 A61P35/00 

Abstract RU 2818486 C1

FIELD: chemistry.

SUBSTANCE: group of inventions relates to organic chemistry and includes an aryl-condensed isoselenazole compound of formula (I), a method for production thereof and use thereof, a pharmaceutical composition containing it, and a method of treatment. In formula (I) A1, A2, A3 and A4 are CH, R1 is C1-6 alkylene, R is selected from hydrogen, halogen, C1-6 alkyl or C1-6 alkoxy.

EFFECT: compound of formula (I), having inhibitory activity on thioredoxin reductase (TrxR).

21 cl, 4 dwg, 7 tbl, 13 ex

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RU 2 818 486 C1

Authors

Tszen, Khuejkhuej

Tszyao, Vensyuan

In, Khanvej

Dates

2024-05-02Published

2021-04-12Filed