MEDICINAL AGENTS CONTAINING N-SULFAMOYL-N'-ARYLPIPERAZINES MEANT FOR PREVENTING OR TREATING OBESITY AND RELATED CONDITIONS Russian patent published in 2010 - IPC C07D295/26 C07D401/04 C07D403/04 C07D405/04 A61K31/495 A61K31/496 A61P3/04 A61P3/06 A61P3/10 A61P9/00 

Abstract RU 2395503 C2

FIELD: chemistry.

SUBSTANCE: invention relates to use of existing and novel N-sulfamoyl- N'-arylpiperazines and their physiologically compatible acid-addition salts of formula I , where Ar denotes a monocyclic or bicyclic C6-C10aryl in which ring carbon atoms are optionally substituted with 1-3 nitrogen or oxygen atoms, and/or where the C6-C10aryl ring system optionally contains 3-5 double bonds, and/or where the C6-C10aryl ring system is optionally substituted with 1 or 2 substitutes which can be identical or different and which can be selected from a group containing halogen, trifluoromethyl, cyano group, nitro group, C1-C4alkyl, C1-C4alkoxy group, C1-C4alkylsulfonyl; and two oxygen atoms which are bonded to two neighbouring carbon atoms of the C6-C10aryl ring system and are bonded by a C1-C2alkylene bridge; or where the C6-C10aryl ring system is substituted with phenyl which can optionally be substituted in the phenyl ring by one substitute which can be selected from a group containing halogen; for preventing or treating obesity and related diseases.

EFFECT: design of a method of obtaining the said compounds and a pharmaceutical composition based on the said compounds.

25 cl, 9 tbl, 5 ex

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RU 2 395 503 C2

Authors

Antel' Jokhen

Gregori Piter-Kolin

Rajnekker Uve

Vurl Mikhaehl'

Shen Uve

Val'Dekk Kharal'D

Firnges Mikhaehl'

Rajkhe Dania

Dates

2010-07-27Published

2005-05-18Filed