FIELD: chemistry.
SUBSTANCE: source of radioactive iodine or radioactive bromine is added to an aqueous solution of an alkaline salt of folic acid so that pH of this solution is approximately 7 in order to obtain a solution which contains folic acid or an iodide or bromide ion. PH of this solution is then lowered to 3.5-4.9 by adding an oxidising agent selected from N-chlorosulfamides of acids in a buffer solution to the said solution. The oxidising agent is mainly chloramines T or chloramines B.
EFFECT: possibility of adding isotopic tags to folic acid through radicals.
2 cl, 2 ex
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Authors
Dates
2010-09-10—Published
2008-11-13—Filed