FIELD: medicine.
SUBSTANCE: what is offered is an analogue of alpha-conotoxin PnIA showing high affinity to a neuronal alpha7 type of the nicotinic receptor and presented by the sequence SEQ ID NO:1. The invention may be used in medicine for developing a therapeutic agent for treating diseases associated with the disordered neuronal alpha7 type of the nicotinic receptor.
EFFECT: use of the invention allows extending the range the substances which appear to be competitive antagonists of the type alpha7 nicotinic receptor.
2 cl, 5 dwg, 1 tbl, 3 ex
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Authors
Dates
2012-07-10—Published
2011-02-10—Filed