PEPTIDE HAVING HIGH AFFINITY TO TYPE ALPHA7 HUMAN NICOTINIC RECEPTOR AND USE THEREOF Russian patent published in 2012 - IPC C12P21/00 A61K38/00 

Abstract RU 2455359 C1

FIELD: medicine.

SUBSTANCE: what is offered is an analogue of alpha-conotoxin PnIA showing high affinity to a neuronal alpha7 type of the nicotinic receptor and presented by the sequence SEQ ID NO:1. The invention may be used in medicine for developing a therapeutic agent for treating diseases associated with the disordered neuronal alpha7 type of the nicotinic receptor.

EFFECT: use of the invention allows extending the range the substances which appear to be competitive antagonists of the type alpha7 nicotinic receptor.

2 cl, 5 dwg, 1 tbl, 3 ex

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RU 2 455 359 C1

Authors

Zhmak Maksim Nurgajanovich

Tsetlin Viktor Ionovich

Kasheverov Igor' Evgen'Evich

Khrushchev Aleksej Jur'Evich

Dates

2012-07-10Published

2011-02-10Filed