METHOD FOR TREATING LUNG CANCER Russian patent published in 2019 - IPC A61B1/267 A61N5/67 A61N5/10 A61K31/216 A61K31/282 A61P35/00 A61M5/158 

Abstract RU 2682293 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to oncology, and can be used to treat lung cancer. For this purpose, endoscopic photodynamic therapy (PDT) is performed. First, the Fotolon photosensitizer is administered in a dose of 1.1 to 1.4 mg/kg of the patient's body weight intravenously over a period of 30 to 40 minutes. 3 hours after the photosensitizer is injected, a laser irradiation of the intrabronchial/intratracheal tumor component is performed. After PDT, cytostatic chemotherapy is administered according to the following scheme: Cisplatin 120 mg on the first day and Etoposide 200 mg on 1, 2, 3 day or Carboplatin 600 mg on the first day and etoposide 200 mg on 1, 2, 3 days. Treatment cycle is repeated 2-3 times with an interval of 21 to 28 days. Then remote radiation therapy in a single focal dose of 2 Gy or 2.4 Gy to a total focal dose of up to 60 or 70 Gy is performed.

EFFECT: method provides improved immediate and long-term results of treatment and local control of inoperable non-small cell lung cancer with obstructive ventilation disorders by reducing the tumor mass, restoring airway patency, reducing the symptomatic manifestations of the disease.

1 cl, 4 dwg, 2 ex

Similar patents RU2682293C2

Title Year Author Number
METHOD OF INTEGRATED TREATMENT OF LOCALLY ADVANCED MALIGNANT BRONCHIAL AND/OR TRACHEAL TUMOURS 2008
  • Arsen'Ev Andrej Ivanovich
  • Barchuk Aleksej Stepanovich
  • Kanaev Sergej Vasil'Evich
  • Gel'Fond Mark L'Vovich
  • Vedenin Jaroslav Olegovich
  • Shulepov Aleksandr Veniaminovich
  • Barchuk Anton Alekseevich
  • Morozova Julija Aleksandrovna
  • Radzhabova Zamira Akhmed-Gadzhievna
RU2372119C1
METHOD OF ORGAN-PRESERVING TREATMENT OF SQUAMOUS CELL CARCINOMA OF ORAL MUCOSA cT1N0M0 WITH DEPTH OF TUMOUR INVASION UP TO 5 mm 2023
  • Sevriukov Feliks Evgenevich
  • Kapinus Viktoriia Nikolaevna
  • Panaseikin Iurii Aleksandrovich
RU2824427C2
METHOD OF TREATING ADVANCED NON-SMALL CELL LUNG CANCER 2014
  • Ivanov Viktor Konstantinovich
  • Mardynskij Jurij Stanislavovich
  • Kashcheev Valerij Vladimirovich
  • Menjajlo Aleksandr Nikolaevich
  • Gulidov Igor' Aleksandrovich
  • Gogolin Danila Vjacheslavovich
  • Ragulin Jurij Aleksandrovich
  • Gorbushin Nikolaj Grigor'Evich
RU2559130C1
METHOD OF COMBINED TREATMENT OF PATIENTS WITH CENTRAL LUNG CANCER AFTER PERFORMING CONDITIONALLY RADICAL SURGICAL INTERVENTIONS 2023
  • Legostaev Vladislav Mikhailovich
  • Leiman Igor Aleksandrovich
  • Kharagezov Dmitrii Akimovich
  • Balitskii Gennadii Vadimovich
  • Nosov Vitalii Aleksandrovich
  • Lazutin Iurii Nikolaevich
  • Stateshnyi Oleg Nikolaevich
  • Milakin Anton Grigorevich
  • Airapetova Tamara Georgievna
  • Gappoeva Madina Aslambekovna
  • Iozefi Kristian Dmitrievich
  • Mirzoian Ellada Armenovna
RU2807897C1
METHOD FOR TREATMENT OF TRANSLABLE CONNECTIVE TISSUE SARCOMA M-1 IN RATS WITH COMBINED IMPACT OF PHOTODYNAMIC THERAPY AND RADIOTHERAPY 2021
  • Kaplan Mikhail Aleksandrovich
  • Drozhzhina Valentina Vladimirovna
  • Arkhipova Liubov Mikhailovna
  • Abramova Olga Borisovna
  • Churikova Tatiana Petrovna
  • Kozlovtseva Ekaterina Aleksandrovna
  • Ivanov Sergei Anatolevich
  • Kaprin Andrei Dmitrievich
RU2763663C2
METHOD OF COMBINED THERAPY FOR CONNECTIVE TISSUE SARCOMA M-1 IN RATS USING A CONJUGATE OF DIPROPOXYBACTERIOPURPURIN WITH DOXORUBICIN 2023
  • Abramova Olga Borisovna
  • Ostroverkhov Petr Vasilevich
  • Drozhzhina Valentina Vladimirovna
  • Kozlovtseva Ekaterina Aleksandrovna
  • Arkhipova Lyubov Mikhajlovna
  • Grin Mikhail Aleksandrovich
  • Ivanov Sergej Anatolevich
  • Kaprin Andrej Dmitrievich
RU2808909C1
METHOD FOR TREATMENT OF RAT M-1 TRANSFERABLE CONNECTIVE TISSUE SARCOMA UNDER COMBINED IMPACT OF PHOTODYNAMIC THERAPY AND RADIATION THERAPY 2021
  • Kaplan Mikhail Aleksandrovich
  • Drozhzhina Valentina Vladimirovna
  • Arkhipova Liubov Mikhailovna
  • Abramova Olga Borisovna
  • Churikova Tatiana Petrovna
  • Kozlovtseva Ekaterina Aleksandrovna
  • Ivanov Sergei Anatolevich
  • Kaprin Andrei Dmitrievich
RU2767272C2
METHOD OF TREATING LUNG CANCER COMPLICATED BY HEMORRHAGE 2010
  • Fokeev Sergej Dmitrievich
  • Maksimenko Aleksej Alekseevich
  • Kazantseva Elena Sergeevna
RU2455921C2
METHOD OF TREATING ORAL CANCER 2019
  • Kaprin Andrej Dmitrievich
  • Ivanov Aleksandr Aleksandrovich
  • Sevryukov Feliks Evgenevich
  • Panasejkin Yurij Aleksandrovich
  • Kaplan Mikhail Aleksandrovich
  • Kapinus Viktoriya Nikolaevna
  • Spichenkova Irina Sergeevna
  • Medvedev Viktor Stepanovich
  • Isaev Pavel Anatolevich
  • Polkin Vyacheslav Viktorovich
  • Semin Dmitrij Yurevich
  • Derbugov Dmitrij Nikolaevich
  • Vasilkov Sergej Valerevich
  • Rozhnov Vitalij Anatolevich
  • Baryshev Vladimir Viktorovich
  • Davydov German Anatolevich
  • Olejnik Natalya Andreevna
RU2713530C2
METHOD FOR APPLYING COMBINED ORGAN-SAVING METHOD FOR TREATING MALIGNANT TUMOR CASES 2005
  • Likhvantseva Vera Gennad'Evna
  • Budzinskaja Marija Viktorovna
  • Merzljakova Oksana Jur'Evna
  • Shevchik Sergej Aleksandrovich
  • Loshchenov Viktor Borisovich
  • Vorozhtsov Georgij Nikolaevich
  • Kuz'Min Sergej Georgievich
RU2286187C1

RU 2 682 293 C2

Authors

Ragulin Yurij Aleksandrovich

Kapinus Viktoriya Nikolaevna

Kaplan Mikhail Aleksandrovich

Gogolin Danil Vyacheslavovich

Gorbushin Nikolaj Grigorevich

Kaprin Andrej Dmitrievich

Ivanov Sergej Anatolievich

Romanko Yurij Sergeevich

Dates

2019-03-18Published

2017-08-28Filed