INDUCTION OF APOPTOSIS IN TUMOUR CELLS, EXPRESSING TOLL-LIKE RECEPTOR Russian patent published in 2010 - IPC A61K31/713 A61K38/21 A61P35/00 

Abstract RU 2401661 C9

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, namely to oncology, and can be used for preparation of medication for treatment of cancer with expression of TLR3 in patient. For this purpose used is TLR3 agonist in combination with type I interferon in low dose. Impact efficiency is conditioned by synergic effect between TLR3 agonist and interferon.

EFFECT: invention allows to affect tumour due to induction of apoptosis in cancer cell TLR3 expressing.

18 cl, 14 ex, 1 dwg

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RU 2 401 661 C9

Authors

Lebek Serzh

Renno Tufik

Salon Brjuno

Kost-Invernitstsi Izabel'

Rissoan Mari-Klotil'D

Dates

2010-10-20Published

2005-07-19Filed