FIELD: medicine.
SUBSTANCE: degree of pathogenicity of enterovirus strains of Coxsackie B virus is determined basing on research of neuropathogenicity of Coxsackie B virus field strain in conditions of one nest of linear mice. Mice are divided on two groups. One is subjected to artificial infection with field strain. Expressed signs of central nervous system affection in mice infected in natural way are fixed. They are compared with characteristic of control strains of Coxsackie B virus prototype and epidemic ones. In case if character of expressed signs of nervous system affection coincides, correspondence of degree of pathogenicity of field strain to interepidemic one is stated.
EFFECT: invention allows to simplify determination of degree of pathogenecity of Coxsackie B virus strain.
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