FIELD: chemistry.
SUBSTANCE: invention relates to a novel carboranyl derivative of fluorinated porphyrins of general formula I , where Ia: M=2H, R=o-CB10H10C-, Ib: M=2M, R=o-C6H5-CB10H10C-, Ic: M=2H, R=-CB11H11 -Cs+, Id: M=Cu, R=-CB11H11 -Cs+, Ie: M=Pd, R=-CB11H11 -Cs+, If: M=2H, R=-CB11H11 -Na+, Ig: M=Cu, R=-CB11H11 -Na+, Ih: M=Pd, R=-CB11H11 -Na+,having photosensitiser properties. The invention also discloses methods for synthesis of said compounds.
EFFECT: compounds which exhibit photosensitiser properties can be used in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) of oncological diseases.
6 cl, 8 ex, 1 tbl
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Authors
Dates
2010-10-27—Published
2008-07-17—Filed