BORATED DERIVATIVES OF FLUORINATED BACTERIOCHLORINES AND THEIR METAL COMPLEXES WITH ANTITUMOR ACTIVITY Russian patent published in 2017 - IPC C07F5/02 C07D487/22 C07F1/08 C07F3/06 C07F15/00 C07F15/04 A61K31/69 A61K31/409 A61K31/555 A61P35/00 

Abstract RU 2615770 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to borated derivatives of fluorinated bacteriochlorines and their metal complexes. The compounds have the general formula I , wherein M=2H, X=Cs (Ia), M=Cu, X=Cs (Ib), M=Zn, X=Cs (Ic), M=Ni, X=Cs (Id), M=Pd, X=Cs (Ie), M=2H, X=Na (If), M=Cu, X=Na (Ig), M=Zn, X=Na (Ih) M=Ni, X=Na (Ii), M=Pd, X=Na (Ij).

EFFECT: compounds can be used as an antitumor agent for boron neutron-capturing therapy and photodynamic cancer therapy.

4 dwg, 10 ex

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RU 2 615 770 C1

Authors

Zajtsev Andrej Viktorovich

Olshevskaya Valentina Antonovna

Petrova Albina Sergeevna

Shtil Aleksandr Albertovich

Kalinin Valerij Nikolaevich

Dates

2017-04-11Published

2015-12-21Filed