COMPOSITION FOR APPLICATION IN PHOTODYNAMIC THERAPY OF CANCER Russian patent published in 2017 - IPC A61K31/409 A61K31/02 A61K9/107 A61P35/00 

FIELD: pharmacology.

SUBSTANCE: composition includes a mixture of perfluorodecalin (PFD) and perfluoro-N-(4-methylcyclohexyl)piperidine (PMCP) as a fluorocarbon phase at PFD and PMC weight ratio of 2:1, in an amount of 5-30 wt %, meso-tetrakis(2,3,5,6-tetrafluoro-4-(1,1-H, H-perfluoroheptyloxy)phenyl)porphyrin or meso-tetrakis(6-H-perfluorohexyl-1)porphyrin in an amount of 0.01-0.04 wt % as a photosensitizer, proxanol-268 in an amount of 2-8 wt % as a stabiliser, NaCl in an amount of 0.7-0.9 wt % and water in an amount of up to 100 wt %.

EFFECT: increased phototoxicity of the photosensitizer with respect to the human colon adenocarcinoma cell line when administered as part of the claimed composition.

2 cl, 2 tbl, 2 ex