APPLICATION OF HUMAN SKIN MELANOMA CELL LINE mel Cher AS POSITIVE MODEL OF VASCULOGENIC MIMICRY Russian patent published in 2010 - IPC C12N5/00 

Abstract RU 2404243 C1

FIELD: medicine.

SUBSTANCE: cell line of human skin melanoma mel Cher possesses stable culture and morphological characteristics, is stored in Specialised collection of cell cultures of Institute of CYTOLOGY RAS under number PKKK ("П") 704"Д". Ctll line of human skin melanoma mel Cher expresses growth factors, such as VEGF, of VEGF receptors of I-st and II-nd types, markers of endothelial cells, such as VIII as.ag., Laminin 5 gamma 2.

EFFECT: obtained cell line is able in stable manner to reproduce process of vasculogenic mimicry in vitro and in vivo.

4 dwg, 3 tbl, 6 ex

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RU 2 404 243 C1

Authors

Grigor'Eva Irina Nikolaevna

Stepanova Evgenija Vladislavovna

Vartanjan Amalija Artashevna

Baryshnikov Anatolij Jur'Evich

Mikhajlova Irina Nikolaevna

Morozova Lidija Fedorovna

Burova Ol'Ga Semenovna

Dates

2010-11-20Published

2009-04-27Filed