FIELD: biotechnology; medicine.
SUBSTANCE: invention relates to use of the subdermal xenografts of cell line of amelanotic human skin melanoma mel Rac with mutation NRAS gene and with adaptation to growth with stable kinetics in immunodeficient Balb/c nude mice for preclinical study of antineoplastic targeted agents.
EFFECT: present invention makes it possible to expand the range of xenografts for preclinical study of antineoplastic targeted agents.
1 cl, 4 dwg, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCTION OF SUBDERMAL XENOGRAFTS OF CELL LINE OF PEOPLE SKIN MELANOMA mel Cher WITH MUTATION V600E BRAF FOR PRECLINICAL STUDY OF ANTINEOPLASTIC TARGETED AGENTS | 2014 |
|
RU2572569C1 |
| METHOD FOR EVALUATING EFFICACY OF RADIOPROTECTIVE DRUGS USING HUMANISED MICE | 2023 |
|
RU2817986C1 |
| METHOD FOR OBTAINING AN ORTHOTOPIC PDX MODEL OF HUMAN BRAIN GLIOBLASTOMA ON IMMUNODEFICIENT MICE FOR PRECLINICAL STUDY OF ANTITUMOR EFFECTS OF CYTOSTATIC DRUGS | 2021 |
|
RU2761892C1 |
| METHOD FOR TREATMENT OF SW620 HUMAN COLON CANCER IN EXPERIMENT | 2017 |
|
RU2665168C1 |
| METHOD FOR OBTAINING AN ORTHOTOPIC PDX MODEL OF SQUAMOUS CELL CARCINOMA OF THE HUMAN ESOPHAGUS FOR THE STUDY OF RADIATION THERAPY IN AN EXPERIMENT | 2021 |
|
RU2760084C1 |
| USE OF ANTISENSE OLIGONUCLEOTIDE 5'-AGCTATCTCCG-3' FROM MOUSE MELANOMA GLUCOSE-6-PHOSPHATE DEHYDROGENASE GENE AS AN ANTITUMOR COMPOUND | 2021 |
|
RU2798243C1 |
| METHOD OF TREATING MELANOMA IN VIVO | 2023 |
|
RU2824428C2 |
| CELL LINE OF HUMAN MELANOMA mel Rac, APPLIED FOR OBTAINING ANTITUMOUR VACCINE | 2009 |
|
RU2402602C1 |
| APPLICATION OF HUMAN SKIN MELANOMA CELL LINE mel Cher AS POSITIVE MODEL OF VASCULOGENIC MIMICRY | 2009 |
|
RU2404243C1 |
| METHOD FOR EXPERIMENTAL BIOTHERAPY OF B16/F10 MELANOMA | 2022 |
|
RU2779698C1 |
