FLUORESCENT CELL LINE mel Kor-TurboRFP AND METHOD FOR USING IT FOR IN VITRO STUDIES IN EXPERIMENTAL ONCOLOGY Russian patent published in 2012 - IPC C12N5/09 

Abstract RU 2458123 C2

FIELD: medicine.

SUBSTANCE: human melanoma cell line mel Kor-TurboRFP possess the stable cultural and morphological characteristics. The cell line is characterised by the expression of melanoma (differentiation) markers -CD63, HMB45, MelanA, Tyrozinase, the absence of class one and two histocompatibility antigens. The cell line is characterised by the expression of red fluorescent protein TurboRFP. The survivor tumour cell count is evaluated after the effect of anti-cancer preparations by measuring the intrinsic fluorescence intensity of the cells mel Kor-TurboRFP in microplate wells.

EFFECT: invention provides higher efficacy and reliability of investigations of anti-cancer preparations.

2 cl, 9 dwg, 3 ex

Similar patents RU2458123C2

Title Year Author Number
FLUORESCENT GLIOMA CELL LINE AND METHOD FOR PRODUCTION THEREOF 2018
  • Shirokov Aleksandr Aleksandrovich
  • Fomin Aleksandr Sergeevich
  • Semyachkina-Glushkovskaya Oksana Valerevna
RU2699754C1
STABLE CELL LINE OF HUMAN OVARIAN ADENOCARCINOMA SKOV-kat 2008
  • Karpenko Dmitrij Vladimirovich
  • Stremovskij Oleg Anatol'Evich
  • Deev Sergej Mikhajlovich
RU2404244C2
APPLICATION OF HUMAN SKIN MELANOMA CELL LINE mel Cher AS POSITIVE MODEL OF VASCULOGENIC MIMICRY 2009
  • Grigor'Eva Irina Nikolaevna
  • Stepanova Evgenija Vladislavovna
  • Vartanjan Amalija Artashevna
  • Baryshnikov Anatolij Jur'Evich
  • Mikhajlova Irina Nikolaevna
  • Morozova Lidija Fedorovna
  • Burova Ol'Ga Semenovna
RU2404243C1
LINE OF CELLS OF HUMAN MELANOMA KG, SECRETING RECOMBINANT GRANULOCYTIC MACROFAGAL COLONY-STIMULATING FACTOR 2008
  • Berezhnoj Aleksej Evgen'Evich
  • Larin Sergej Sergeevich
  • Gnuchev Nikolaj Vasil'Evich
  • Georgiev Georgij Pavlovich
  • Zakharova Elena Sergeevna
  • Baryshnikov Anatolij Jur'Evich
  • Demidov Lev Vadimovich
  • Mikhajlova Irina Nikolaevna
  • Burova Ol'Ga Semenovna
  • Morozova Lidija Fedorovna
  • Kozlov Aleksej Mikhajlovich
RU2362805C1
HUMAN MELANOMA CELLULAR LINE mel Kor USED IN PREPARING ANTITUMOR VACCINE 2005
  • Mikhajlova Irina Nikolaevna
  • Baryshnikov Anatolij Jur'Evich
  • Morozova Lidija Fedorovna
  • Burova Ol'Ga Semenovna
  • Demidov Lev Vadimovich
  • Kozlov Aleksej Mikhajlovich
  • Larin Sergej Sergeevich
  • Georgiev Georgij Pavlovich
  • Vorozhtsov Georgij Nikolaevich
  • Gnuchev Nikolaj Vasil'Evich
RU2287578C1
METHOD FOR INCREASING IMMUNOGENICITY OF WHOLE-CELL ANTI-CANCER VACCINE 2010
  • Manina Irina Vladimirovna
  • Mikhajlova Irina Nikolaevna
  • Kozlov Aleksej Mikhajlovich
  • Baryshnikov Anatolij Jur'Evich
RU2458120C1
CELL PRODUCT FOR LOADING AND ACTIVATION OF HUMAN DENDRITE CELLS 2019
  • Baldueva Irina Aleksandrovna
  • Danilova Anna Borisovna
  • Nekhaeva Tatyana Leonidovna
  • Avdonkina Natalya Aleksandrovna
  • Emelyanova Natalya Viktorovna
  • Belyaev Aleksej Mikhajlovich
RU2714208C1
HUMAN SKIN MELANOMA CELL LINE mel-Alx-LP 2022
  • Prosekina Elizaveta Andreevna
  • Murashkina Anna Andreevna
  • Karpov Artem Evgenevich
  • Fedorutseva Elena Yurevna
  • Artemeva Anna Sergeevna
  • Malek Anastasiya Valerevna
RU2796357C1
APPLICATION OF PROTEIN EXTRACT AS ANTIPROLIFERATIVE AND CYTOTOXIC AGENT 2017
  • Novik Tamara Samuilovna
  • Koveshnikova Elena Ivanovna
  • Berezhko Vera Kuzminichna
  • Kamyshnikov Oleg Yurevich
  • Chukina Svetlana Ivanovna
  • Danilova Tamara Ivanovna
  • Napisanova Lyudmila Aleksandrovna
  • Tkhakakhova Amina Aslanovna
  • Uspenskij Aleksandr Vitalevich
  • Arkhipov Ivan Alekseevich
RU2671632C1
STABLE HUMAN BREAST CANCER CARCINOMA CELL LINE SKBR-KAT 2018
  • Peskova Nina Nikolaevna
  • Sokolova Evgeniya Aleksandrovna
  • Balalaeva Irina Vladimirovna
  • Sencha Lyudmila Mikhajlovna
  • Gurev Evgenij Leonidovich
  • Kutova Olga Mikhajlovna
RU2709675C1

RU 2 458 123 C2

Authors

Meerovich Irina Gennad'Evna

Zherdeva Viktorija Vjacheslavovna

Arslanbaeva Ljajsan Ravilovna

Savitskij Aleksandr Pavlovich

Burova Ol'Ga Semenovna

Mikhajlova Irina Nikolaevna

Morozova Lidija Fedorovna

Baryshnikov Anatolij Jur'Evich

Dates

2012-08-10Published

2009-10-13Filed