METHOD OF DIAGNOSING VAGINAL ATROPHY IN WOMEN OF REPRODUCTIVE AGE IN STATE OF POST-OVARIECTOMY Russian patent published in 2010 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: there is claimed method of diagnosing atrophic process in vagina in women after radical operations on organs of small pelvis. Immunogystochemical analysis of vaginal biopsy material is carried out with calculation of number and diametre of vessels in them, for which purpose biopsy of vagina in its middle third with sampling of biopsy material of size 0.5x0.5x0.3 cm is performed, after that, biopsy material is fixed in neutral 10% formalin for 18 hours with further passing in isopropanole and pouring into paraffin, after that staining of deparaffinated cuts with hematoxylin and eosin is carried out in accordance with classical methods with preliminary disclosing of antigen in citrate buffers for CD34, result of reaction is identified by nuclear cell staining, number and size of vessels, visualised by means of CD34, and in case of vessels of medium and large diametre with area 3-10 mm² are present, norm is determined, and if vessels with area 2 mm² and less are present, vaginal atrophy is diagnosed.

EFFECT: increase of diagnostics efficiency.

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