FIELD: medicine.
SUBSTANCE: in order to diagnose degree of gestosis severity index of expression of apoptosis markers p53 and bcl-2 is determined. If index of p53 expression equals or is higher than 2.4 standard units and bcl-2 equal or is higher than 2.2 standard units, gestosis of severe degree is diagnosed. If index of p53 expression equals 2.0-2.39 standard units and bcl-2 equals 1.8-2.19 standard units, gestosis of light degree of severity is diagnosed.
EFFECT: application of invention allows to perform at modern level objective patomorphological analysis of placenta and carry out diagnostics of undetected in clinic gestosis and differential diagnostics of its severity degrees with high accuracy.
6 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF MORPHOLOGICAL DIAGNOSIS OF THE SEVERITY OF PREECLAMPSIA | 2017 |
|
RU2682251C1 |
| METHOD FOR PREECLAMPSIA SEVERITY DIAGNOSTICS BASED ON EVALUATION OF DNA-RECOGNIZING DAI-1 RECEPTORS EXPRESSION IN PLACENTAL TISSUE | 2017 |
|
RU2641029C1 |
| DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR PRIMARY PLACENTAL INSUFFICIENCY | 2013 |
|
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| DIAGNOSTIC TECHNIQUE OF PREECLAMPSIA IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION | 2012 |
|
RU2483311C1 |
| DIAGNOSTIC TECHNIQUE FOR PREMATURE DETACHMENT OF NORMALLY LOCATED PLACENTA | 2015 |
|
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| METHOD FOR DIAGNOSING CHRONIC PLACENTAL INSUFFICIENCY CASES | 2006 |
|
RU2313795C1 |
| DIAGNOSTIC TECHNIQUE FOR FOETAL AND NEONATAL LUNG DEVELOPMENT DELAY | 2013 |
|
RU2516889C1 |
| METHOD FOR EARLY DIAGNOSTICS OF SECONDARY PLACENTAL DEFICIENCY | 2000 |
|
RU2193864C2 |
| RETROSPECTIVE (POSTNATAL) EXPRESS DIAGNOSTIC TECHNIQUE FOR PLACENTAL INSUFFICIENCY TO DETECT NEWBORN GROUP WITH HIGH RISK OF PATHOLOGY DEVELOPMENT IN NEONATAL PERIOD | 2007 |
|
RU2361213C2 |
| METHOD OF GESTOSIS DIAGNOSTICS WITH PREGNANT | 2010 |
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RU2438570C1 |
