FIELD: medicine.
SUBSTANCE: bronchial epithelium of dead fetuses or newborns of 22-40 weeks of gestation is examined by immunohistochemical method; there are also evaluated expression indices of epidermal growth factor (EGF) and insulin-like growth factor I (ILGF-I). If the relation of the EGF expression index to the ILGF-I expression index is more than 1.0, a morphofunctional maturity of the lungs is diagnosed, and if the relation is less than 1.0, the lung development delay is stated.
EFFECT: technique enables diagnosing the lung tissue development delay without regard to the antropometric parameters and gestation term, providing the objective death mechanism of the foetuses and newborns.
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Authors
Dates
2014-05-20—Published
2013-02-20—Filed