FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely, to pathoanatomy, and can be used for the morphological diagnosis of the severity of preeclampsia. Invention is a method of morphological diagnosis of the severity of preeclampsia by immunohistological analysis of the basal decidual membrane of the placenta, characterized in that cytotrophoblast determines the expression index of transcription marker (TFAM) of mitochondrial DNA and when the value of the expression index of TFAM is from 0.32 to 0.4 cu moderate preeclampsia is diagnosed, and with a TFAM expression index of 0.31 cu or less severe pre-eclampsia is diagnosed.
EFFECT: technical result of the proposed method is the expansion of the spectrum of morphological diagnostic methods for determining the severity of preeclampsia.
1 cl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF MORPHOLOGICAL DIAGNOSTICS OF SEVERITY DEGREE OF GESTOSIS | 2009 |
|
RU2407008C1 |
METHOD OF DIAGNOSTICS OF SEVERITY OF PRE-ECLAMPSIA ON THE BACKGROUND OF CHRONIC ARTERIAL HYPERTENSION IN PREGNANT WOMEN | 2023 |
|
RU2804645C1 |
METHOD FOR PREECLAMPSIA SEVERITY DIAGNOSTICS BASED ON EVALUATION OF DNA-RECOGNIZING DAI-1 RECEPTORS EXPRESSION IN PLACENTAL TISSUE | 2017 |
|
RU2641029C1 |
METHOD FOR DIAGNOSING SEVERITY OF PREECLAMPSIA WITH UNDERLYING CHRONIC ARTERIAL HYPERTENSION IN PREGNANT WOMEN | 2023 |
|
RU2815220C1 |
DIAGNOSTIC TECHNIQUE FOR PREMATURE DETACHMENT OF NORMALLY LOCATED PLACENTA | 2015 |
|
RU2601625C1 |
DIAGNOSTIC TECHNIQUE OF PREECLAMPSIA IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION | 2012 |
|
RU2483311C1 |
DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR PRIMARY PLACENTAL INSUFFICIENCY | 2013 |
|
RU2535011C2 |
METHOD FOR PREDICTING THE RISK OF DEVELOPMENT OF PREECLAMPSIA IN PREGNANT WOMEN WITH FETAL GROWTH RESTRICTION SYNDROME | 2021 |
|
RU2754956C1 |
METHOD FOR PREDICTING THE RISK OF DEVELOPING PREECLAMPSIA BASED ON MOLECULAR GENETIC ANALYSIS | 2021 |
|
RU2775433C1 |
METHOD FOR PREVENTING PREECLAMPSIA IN PATIENTS WITH AN AGGRAVATED OBSTETRIC ANAMNESIS | 2016 |
|
RU2663593C2 |
Authors
Dates
2019-03-18—Published
2017-12-19—Filed