ESTER DERIVATIVE OF 2-AMINO-BICYCLO[3,1,0]HEXANE-2,6-DICARBOXYLIC ACID Russian patent published in 2011 - IPC C07C229/50 A61K31/215 A61P25/00 

Abstract RU 2409557 C2

FIELD: chemistry.

SUBSTANCE: invention relates to an ester derivative of 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid of formula (II) or the corresponding pharmaceutical salt, having group II metabotropic glutamate receptor antagonist properties. In formula X denotes fluorine, Y denotes 3,4-di-chlorobenzyloxy, R2 denotes hydrogen and R1 denotes an alkyl group selected from n-butyl, n-pentyl, n-hexyl, n-heptyl, n-octyl, n-decyl, 3-methylbutyl, 4-methylpenyl, 5-methylhexyl and 6-methylheptyl. The invention also relates to a medicinal agent and to use of formula (II) compounds as a medicinal agent for treating depression symptoms.

EFFECT: high yield.

14 cl, 4 tbl, 10 ex

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RU 2 409 557 C2

Authors

Jasukhara Akito

Sakagami Kazunari

Okhta Khirosi

Nakazato Atsuro

Dates

2011-01-20Published

2004-06-25Filed